Solubility is the capacity of the solvent to dissolve a solute. Solutes may differ in both the extent and the rate at which they dissolve in a solvent. The solubility of one substance in another is a measure of the degree of molecular mixing between the two pure substances at thermodynamic equilibrium. The composition of a saturated solution, expressed as a proportion of a designated solute in a designated solvent, represents this thermodynamic limit of solubility. Solubility may be stated in units of concentration such as molality, mole fraction, mole ratio, weight/volume, or weight/weight. Solubility can be expressed in absolute as well as relative terms. Relative measures of the solubility of Active Pharmaceutical Ingredients (APIs) are important for predicting the drug delivery characteristics of a dosage form and characterizing a drug as either high solubility or low solubility in the biopharmaceutics classification system (BCS).
Accurate determination of the solubility of pharmaceutical materials is important for understanding both quality control and drug delivery issues for pharmaceutical formulations. Also understanding the solubility profile of the Active Pharmaceutical Ingredients helps in getting the biowaivers.
Most of the pharmacopoeias across the globe provides a solubility descriptive terms like soluble, freely soluble, sparingly soluble, insoluble etc. Please find below the table presenting the solubility descriptions and the part of solvents required to dissolve the solutes:
Descriptive term | Parts of Solvent required for 1 Part of Solute |
---|---|
Very soluble | Less than 1 |
Freely soluble | From 1 to 10 |
Soluble | From 10 to 30 |
Sparingly soluble | From 30 to 100 |
Slightly soluble | From 100 to 1000 |
Very slightly soluble | From 1000 to 10,000 |
Practically insoluble, or Insoluble | 10,000 or more |
Referring to various pharmacopoeia viz. USP, BP, IP, EP etc. we have prepared a table of various APIs and other pharmaceutical ingredients and their solubility profile in various solvents. This table may act as a ready reckoner.
Product Name | Water | Ethanol | Ether | Chloroform | Methanol | Acetone | Dichloromethane |
---|---|---|---|---|---|---|---|
Abacavir Sulphate | Soluble | X | X | X | X | X | X |
Abiraterone Acetate | X | X | X | X | X | X | Soluble |
Acacia and Acacia Powder | Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Acamprosate Calcium | Freely Soluble | Practically Insoluble | X | X | X | X | Practically Insoluble |
Acarbose | Very Soluble | X | X | X | Soluble | X | Practically Insoluble |
Acebutolol Hydrochloride | Freely Soluble | Freely Soluble | Practically Insoluble | X | X | Very Slightly Soluble | Very Slightly Soluble |
Aceclofenac | Practically Insoluble | Soluble | X | X | X | Freely Soluble | X |
Acepromazine Maleate | Soluble | Soluble | Slightly Soluble | X | X | X | Freely Soluble |
Acesulphame potassium | Soluble | Very Slightly Soluble | X | X | X | Very Slightly Soluble | X |
Glacial Acetic Acid | Soluble | Soluble | Soluble | X | X | X | Soluble |
Acetazolamide | Very Slightly Soluble | Slightly Soluble | X | X | X | X | X |
Aciclovir | Slightly Soluble | Very Slightly Soluble | X | X | X | X | Freely Soluble |
Acitretin | Practically Insoluble | Slightly Soluble | X | Very Slightly Soluble | X | Slightly Soluble | X |
Adefovir Dipivoxil | X | Freely Soluble | X | Freely Soluble | X | X | X |
Adenosine | Soluble | Practically Insoluble | X | X | X | X | Practically Insoluble |
Adipic Acid | Soluble | Freely Soluble | X | X | Freely Soluble | Soluble | X |
Adrenaline Tartrate | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Adrenaline | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Agomelatine | X | X | X | Soluble | Soluble | X | Soluble |
Albendazole | X | X | X | Slightly Soluble | Very Slightly Soluble | X | X |
Alfuzosin Hydrochloride | Freely Soluble | Sparingly Soluble | X | X | X | X | Practically Insoluble |
Alginic Acid | Practically Insoluble | Very Slightly Soluble | X | X | X | X | X |
Allantoin | Slightly Soluble | Very Slightly Soluble | X | X | X | X | X |
Allopurinol | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Aloes | Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Alprazolam | Practically Insoluble | Soluble | X | Freely Soluble | X | Sparingly Soluble | X |
Alprostadil | X | Freely Soluble | X | X | X | Soluble | X |
Aluminium Hydroxide, Dried | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Aluminium Magnesium Silicate | Practically Insoluble | X | X | X | X | X | X |
Amantadine Hydrochloride | Freely Soluble | Freely Soluble | Practically Insoluble | Soluble | X | X | X |
Ambrisentan | X | X | X | X | X | X | X |
Ambroxol Hydrochloride | Sparingly Soluble | X | X | X | Soluble | X | Practically Insoluble |
Amikacin | Sparingly Soluble | X | X | X | X | X | X |
Amikacin Sulphate | Freely Soluble | X | Practically Insoluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X |
Amiloride Hydrochloride | Slightly Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Aminocaproic Acid | Freely Soluble | Slightly Soluble | X | Practically Insoluble | Slightly Soluble | X | X |
Aminophylline | Freely Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Amiodarone Hydrochloride | Very Slightly Soluble | Sparingly Soluble | X | X | X | X | Freely Soluble |
Amisulpride | Practically Insoluble | Sparingly Soluble | X | X | X | X | Freely Soluble |
Amitraz | Practically Insoluble | X | X | X | X | Freely Soluble | X |
Amitriptyline Hydrochloride | Freely Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | Freely Soluble | X | X |
Amlodipine Besylate | Slightly Soluble | Sparingly Soluble | X | X | Freely Soluble | X | X |
S-Amlodipine | X | X | X | X | Soluble | X | X |
Ammonium Chloride | Freely Soluble | Sparingly Soluble | X | X | X | X | X |
Amodiaquine Hydrochloride | Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Amorolfine Hydrochloride | Soluble | Soluble | X | X | X | X | X |
Amoxycillin Sodium | Very Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | Very Slightly Soluble | X |
Amoxycillin Trihydrate | Slightly Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | Slightly Soluble | X | X |
Amphotericin B | Practically Insoluble | Practically Insoluble | X | X | Slightly Soluble | X | X |
Ampicillin | Sparingly Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Ampicillin Sodium | Freely Soluble | X | Practically Insoluble | Sparingly Soluble | X | Sparingly Soluble | X |
Ampicillin Trihydrate | Slightly Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Amprolium Hydrochloride | Freely Soluble | Slightly Soluble | Very Slightly Soluble | X | X | X | Practically Insoluble |
Alpha Amylase | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Analgin | Very Soluble | Soluble | X | X | X | X | Practically Insoluble |
Anastrozole | X | Freely Soluble | X | X | Freely Soluble | Freely Soluble | X |
Aprepitant | Practically Insoluble | Sparingly Soluble | X | X | X | X | X |
Aprotinin | Soluble | X | X | X | X | X | X |
Arbidol Hydrochloride | X | X | X | X | X | X | X |
Arginine | Freely Soluble | Sparingly Soluble | Practically Insoluble | X | X | X | X |
Aripiprazole | Practically Insoluble | X | X | X | X | Sparingly Soluble | X |
Armodafinil | Practically Insoluble | X | X | X | X | X | X |
Arteether | X | X | X | X | Soluble | Soluble | X |
Artemether | Practically Insoluble | X | X | X | X | Very Soluble | Very Soluble |
Arterolane Maleate | Slightly Soluble | Freely Soluble | X | X | Freely Soluble | X | X |
Artesunate | X | Slightly Soluble | Practically Insoluble | X | X | X | X |
Ascorbic Acid | Freely Soluble | Freely Soluble | X | X | X | X | Practically Insoluble |
Ascorbyl Palmitate | Practically Insoluble | X | X | X | Freely Soluble | X | Soluble |
Asenapine Maleate | Practically Insoluble | Slightly Soluble | X | X | X | X | Practically Insoluble |
Aspartame | Slightly Soluble | Freely Soluble | Soluble | Soluble | X | X | X |
Aspirin | Slightly Soluble | X | X | X | X | X | X |
Atazanavir Sulphate | Sparingly Soluble | X | X | X | Sparingly Soluble | X | X |
Atenolol | Sparingly Soluble | Soluble | Practically Insoluble | X | X | X | Slightly Soluble |
Atomoxetine Hydrochlroide | Soluble | X | X | X | Freely Soluble | X | Freely Soluble |
Atorvastatin Calcium | Very Slightly Soluble | Slightly Soluble | X | X | Freely Soluble | X | X |
Atosiban Acetate | Soluble | X | X | X | X | X | X |
Atracurium Besilate | Soluble | Very Soluble | X | X | X | X | X |
Atropine Methonitrate | Freely Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Atropine Sulphate | Very Soluble | Freely Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Azacitidine | X | X | X | X | X | X | X |
Azathioprine | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Azelastine Hydrochloride | Sparingly Soluble | Soluble | X | X | X | X | Soluble |
Azelnidipine | Sparingly Soluble | X | X | X | Slightly Soluble | Freely Soluble | X |
Azithromycin | Practically Insoluble | Freely Soluble | X | X | X | X | Freely Soluble |
Bacitracin | Freely Soluble | Freely Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Bacitracin Zinc | Slightly Soluble | Slightly Soluble | Very Slightly Soluble | Practically Insoluble | X | X | X |
Baclofen | Slightly Soluble | Very Slightly Soluble | X | X | X | X | X |
Bambuterol Hydrochloride | Freely Soluble | Soluble | X | X | X | X | X |
Barium Sulphate | Practically Insoluble | X | X | X | X | X | X |
Beclomethasone Dipropionate | Practically Insoluble | Sparingly Soluble | Soluble | Freely Soluble | X | Freely Soluble | X |
Beeswax, White | Practically Insoluble | Soluble | Soluble | X | X | X | X |
Beeswax, Yellow | Practically Insoluble | Soluble | X | X | X | X | X |
Benazepril Hydrochloride | Slightly Soluble | Freely Soluble | X | Practically Insoluble | X | X | X |
Bendamustine Hydrochloride | Slightly Soluble | X | X | Practically Insoluble | Freely Soluble | X | X |
Bentonite | Practically Insoluble | X | X | X | X | X | X |
Benzalkonium Chloride | Very Soluble | Very Soluble | X | X | X | X | X |
Benzalkonium Chloride Solution | Soluble | Soluble | Practically Insoluble | X | X | X | X |
Benzathine Penicillin | Very Slightly Soluble | Slightly Soluble | X | Very Slightly Soluble | X | X | X |
Benzhexol Hydrochloride | Slightly Soluble | Soluble | Soluble | Soluble | Soluble | X | X |
Benzocaine | Very Slightly Soluble | Freely Soluble | X | Freely Soluble | X | X | X |
Benzoic Acid | Slightly Soluble | Freely Soluble | X | Freely Soluble | X | X | X |
Hydrous Benzoyl Peroxide | Sparingly Soluble | Sparingly Soluble | Practically Insoluble | X | X | Soluble | X |
Benzyl Alcohol | Soluble | X | Practically Insoluble | X | X | X | X |
Benzyl Benzoate | Practically Insoluble | Soluble | X | Soluble | X | X | X |
Benzylpenicillin Potassium | Very Soluble | X | X | Practically Insoluble | X | X | X |
Benzylpenicillin Sodium | Very Soluble | X | X | Practically Insoluble | X | X | X |
Betahistine Hydrochloride | Very Soluble | Soluble | X | X | X | X | X |
Betahistine Mesylate | Very Soluble | Freely Soluble | X | X | X | X | X |
Betamethasone | Practically Insoluble | Sparingly Soluble | X | Very Slightly Soluble | X | X | X |
Betamethasone Dipropionate | Practically Insoluble | Sparingly Soluble | X | Freely Soluble | X | Freely Soluble | Freely Soluble |
Betamethasone Sodium Phosphate | Freely Soluble | Slightly Soluble | X | Practically Insoluble | X | X | Practically Insoluble |
Betamethasone Valerate | Practically Insoluble | Soluble | X | Freely Soluble | X | X | X |
Betaxolol Hydrochlroide | Very Soluble | Freely Soluble | X | X | X | X | Soluble |
Bezafibrate | X | Sparingly Soluble | X | X | X | Sparingly Soluble | X |
Biapenem | Slightly Soluble | X | X | X | X | X | X |
Bicalutamide | X | X | X | X | Sparingly Soluble | X | X |
Bifonazole | Practically Insoluble | Sparingly Soluble | X | X | X | X | X |
Biperiden Hydrochloride | Practically Insoluble | Slightly Soluble | Practically Insoluble | X | X | X | Very Slightly Soluble |
Bisacodyl | Practically Insoluble | Sparingly Soluble | Slightly Soluble | Soluble | Sparingly Soluble | Soluble | X |
Bismuth Subcarbonate | X | Practically Insoluble | Practically Insoluble | X | X | X | X |
Bisoprolol Fumarate | X | X | X | Freely Soluble | Very Soluble | Slightly Soluble | X |
Bleomycin Sulphate | Very Soluble | X | X | X | X | X | X |
Boric Acid | Soluble | Soluble | X | X | X | X | X |
Bortezomib | X | X | X | X | Sparingly Soluble | X | X |
Bosentan Monohydrate | X | X | X | X | X | X | X |
Brimonidine Tartrate | Soluble | X | X | X | Soluble | X | X |
Brinzolamide | Practically Insoluble | X | X | X | Slightly Soluble | X | X |
Bromhexine Hydrochloride | Practically Insoluble | Sparingly Soluble | X | Slightly Soluble | Sparingly Soluble | X | X |
Bromocriptine Mesylate | Practically Insoluble | Soluble | X | X | Freely Soluble | X | Sparingly Soluble |
Bronopol | Soluble | Soluble | Slightly Soluble | Slightly Soluble | X | Slightly Soluble | X |
Buclizine Hydrochloride | Practically Insoluble | Slightly Soluble | X | X | X | X | X |
Budesonide | X | Sparingly Soluble | X | X | X | X | Freely Soluble |
Bumetanide | Practically Insoluble | Soluble | X | X | X | Soluble | Slightly Soluble |
Bupivacaine Hydrochloride | Soluble | Freely Soluble | X | Slightly Soluble | X | Slightly Soluble | X |
Buprenorphine Hydrochloride | Slightly Soluble | X | X | Slightly Soluble | Soluble | X | X |
Buserelin | Sparingly Soluble | X | X | X | X | X | X |
Buspirone Hydrochloride | Freely Soluble | X | X | X | Freely Soluble | Practically Insoluble | X |
Busulphan | Very Slightly Soluble | Very Slightly Soluble | Very Slightly Soluble | Freely Soluble | X | Freely Soluble | X |
Butylated Hydroxytoluene | Practically Insoluble | Freely Soluble | Very Slightly Soluble | Very Soluble | Freely Soluble | Very Soluble | X |
Butylparaben | X | Freely Soluble | X | Freely Soluble | X | Freely Soluble | X |
Cabergoline | Practically Insoluble | Freely Soluble | X | X | X | X | X |
Caffeine | Sparingly Soluble | Sparingly Soluble | Slightly Soluble | Freely Soluble | X | X | X |
Calamine | Practically Insoluble | X | X | X | X | X | X |
Alphacalcidol | Practically Insoluble | Freely Soluble | X | X | X | X | X |
Calcipotriol Anhydrous | Practically Insoluble | Freely Soluble | X | X | X | X | Slightly Soluble |
Calcitriol | Practically Insoluble | Freely Soluble | X | X | X | X | X |
Calcium Carbonate | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Calcium Chloride | Freely Soluble | Freely Soluble | X | X | X | X | X |
Calcium Dobesilate Monohydrate | Freely Soluble | Freely Soluble | X | X | X | X | Practically Insoluble |
Calcium Folinate | Very Soluble | Practically Insoluble | X | X | X | X | X |
Calcium Gluconate | Freely Soluble | Practically Insoluble | X | X | X | X | X |
Calcium Lactate | Freely Soluble | Very Slightly Soluble | X | X | X | X | X |
Calcium Levulinate | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Calcium Pantothenate | Freely Soluble | Slightly Soluble | Practically Insoluble | X | X | X | X |
Dibasic Calcium Phosphate | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Tribasic Calcium Phosphate | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Calcium Stearate | Practically Insoluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Capecitabine | Sparingly Soluble | X | X | X | Freely Soluble | X | X |
Capreomycin sulphate | Freely Soluble | X | X | X | X | X | X |
Captopril | Freely Soluble | Freely Soluble | X | X | Freely Soluble | X | X |
Carbamazepine | Practically Insoluble | Sparingly Soluble | Practically Insoluble | X | X | Sparingly Soluble | X |
Carbenicillin Sodium | Freely Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Carbenoxolone Sodium | Freely Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Carbidopa | Slightly Soluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble |
Carbimazole | Slightly Soluble | Sparingly Soluble | Slightly Soluble | Freely Soluble | X | Soluble | X |
Carbomers | Soluble | Soluble | X | X | X | X | X |
Carboplatin | Soluble | X | X | X | X | X | X |
Carboprost Trometamol | Soluble | X | X | X | X | X | X |
Carboxymethylcellulose Calcium | X | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Carboxymethylcellulose Sodium | X | Practically Insoluble | Practically Insoluble | X | X | X | X |
Carisoprodol | X | Freely Soluble | Very Slightly Soluble | Freely Soluble | X | Freely Soluble | X |
Carmustine | X | X | Freely Soluble | X | X | X | X |
Carnauba Wax | Practically Insoluble | Practically Insoluble | X | Soluble | X | X | X |
Carprofen | Practically Insoluble | X | X | X | Soluble | Freely Soluble | X |
Carvedilol | Practically Insoluble | Slightly Soluble | X | X | X | X | X |
Cefaclor | X | X | X | X | Practically Insoluble | X | Practically Insoluble |
Cefadroxil | Slightly Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Cefamandole Nafate | Practically Insoluble | X | X | X | Sparingly Soluble | X | X |
Cefazolin Sodium | Freely Soluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Cefdinir | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Cefepime Hydrochloride | Freely Soluble | X | X | X | Freely Soluble | X | Practically Insoluble |
Cefixime | Practically Insoluble | Sparingly Soluble | X | X | Soluble | X | X |
Cefoperazone Sodium | Freely Soluble | Slightly Soluble | X | X | Soluble | X | X |
Cefotaxime Sodium | Freely Soluble | X | X | X | X | X | X |
Cefpirome Sulphate | Freely Soluble | X | X | X | X | X | X |
Cefpodoxime Proxetil | Very Slightly Soluble | X | Slightly Soluble | X | Soluble | Soluble | X |
Ceftazidime | Slightly Soluble | X | X | X | Slightly Soluble | Practically Insoluble | X |
Ceftiofur sodium | Freely Soluble | X | X | X | X | X | X |
Ceftriaxone Sodium | Freely Soluble | Very Slightly Soluble | X | X | Sparingly Soluble | X | X |
Ceftizoxime Sodium | Freely Soluble | X | X | X | X | X | X |
Cefuroxime Axetil | Practically Insoluble | Slightly Soluble | Practically Insoluble | Soluble | Soluble | Freely Soluble | X |
Cefuroxime Sodium | Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Celecoxib | Practically Insoluble | Freely Soluble | X | X | X | X | Soluble |
Celiprolol Hydrochloride | Freely Soluble | Soluble | X | X | Freely Soluble | X | Very Slightly Soluble |
Cellulose Acetate Phthalate | Practically Insoluble | Practically Insoluble | X | X | X | Freely Soluble | X |
Cephalexin | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Cephaloridine | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Cetirizine Hydrochloride | Freely Soluble | X | X | X | X | Practically Insoluble | Practically Insoluble |
Cetostearyl Alcohol | Practically Insoluble | Soluble | Freely Soluble | X | X | X | X |
Cetrimide | Freely Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Cetyl Alcohol | Practically Insoluble | Sparingly Soluble | Freely Soluble | X | X | X | X |
Cetyl Palmitate | Practically Insoluble | X | X | X | X | X | X |
Activated Char | X | X | X | X | X | X | X |
Chlorambucil | Practically Insoluble | Freely Soluble | X | Freely Soluble | X | Freely Soluble | X |
Chloramphenicol | Slightly Soluble | Freely Soluble | Slightly Soluble | X | X | X | X |
Chloramphenicol Palmitate | Practically Insoluble | Slightly Soluble | Soluble | Soluble | X | Soluble | X |
Chloramphenicol Sodium Succinate | Freely Soluble | Freely Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Chlorbutol | Slightly Soluble | Freely Soluble | Freely Soluble | Freely Soluble | X | X | X |
Chlorcyclizine Hydrochloride | Freely Soluble | Soluble | X | X | X | X | X |
Chlordiazepoxide | Practically Insoluble | Sparingly Soluble | Slightly Soluble | X | X | X | X |
Chlorhexidine Acetate | X | Soluble | X | X | X | X | X |
Chlorhexidine Gluconate Solution | Soluble | Soluble | X | X | X | Soluble | X |
Chlorhexidine Hydrochloride | Sparingly Soluble | Very Slightly Soluble | X | X | X | X | X |
Chlorinated Lime | Soluble | Soluble | X | X | X | X | X |
Chlorocresol | Slightly Soluble | Very Soluble | Freely Soluble | X | X | X | X |
Chloroform | Slightly Soluble | Soluble | Soluble | X | X | X | X |
Chloroquine Phosphate | Freely Soluble | Very Slightly Soluble | Very Slightly Soluble | Very Slightly Soluble | Very Slightly Soluble | X | X |
Chloroquine Sulphate | Freely Soluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | Freely Soluble | X | X |
Chlorothiazide | Very Slightly Soluble | Slightly Soluble | X | X | X | Sparingly Soluble | X |
Chloroxylenol | Very Slightly Soluble | Freely Soluble | Soluble | X | X | X | X |
Chlorpheniramine Maleate | Freely Soluble | Soluble | Slightly Soluble | Soluble | X | X | X |
Chlorpromazine Hydrochloride | Very Soluble | Freely Soluble | Practically Insoluble | Soluble | X | X | X |
Chlorpropamide | Practically Insoluble | Soluble | Slightly Soluble | Freely Soluble | X | Freely Soluble | X |
Chlorthalidone | Practically Insoluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | Soluble | X | X |
Cholecalciferol | Practically Insoluble | Freely Soluble | Freely Soluble | Freely Soluble | X | Freely Soluble | X |
Cholecalciferol Concentrate (Powder Form) | Practically Insoluble | X | X | X | X | X | X |
Choline Fenofibrate | Freely Soluble | X | X | X | X | X | X |
Chlortetracycline Hydrochloride | Slightly Soluble | Slightly Soluble | X | X | X | X | X |
Chorionic Gonadotrophin | Soluble | Practically Insoluble | X | X | X | Practically Insoluble | X |
Chymotrypsin | Sparingly Soluble | X | X | X | X | X | X |
Ciclesonide | Practically Insoluble | X | X | X | Freely Soluble | X | Very Soluble |
Cilastatin Sodium | Very Soluble | Slightly Soluble | X | X | Very Soluble | Practically Insoluble | Practically Insoluble |
Cilnidipine | Freely Soluble | X | X | X | Sparingly Soluble | Freely Soluble | X |
Cilostazol | Practically Insoluble | Slightly Soluble | X | Freely Soluble | Slightly Soluble | X | X |
Cimetidine | Slightly Soluble | Soluble | Practically Insoluble | Practically Insoluble | Freely Soluble | X | Practically Insoluble |
Cinacalcet Hydrochloride | X | X | X | X | X | X | X |
Cinnarizine | Practically Insoluble | Slightly Soluble | X | X | Slightly Soluble | Soluble | Freely Soluble |
Ciprofloxacin | Practically Insoluble | Very Slightly Soluble | X | X | X | X | Very Slightly Soluble |
Ciprofloxacin Hydrochloride | Soluble | Very Slightly Soluble | X | X | Slightly Soluble | Practically Insoluble | Practically Insoluble |
Cisplatin | Slightly Soluble | Practically Insoluble | X | X | X | X | X |
Citalopram Hydrobromide. | X | Very Soluble | X | Very Soluble | X | X | X |
Citicoline Sodium | Freely Soluble | X | X | X | Practically Insoluble | X | X |
Citric Acid | Very Soluble | Freely Soluble | Sparingly Soluble | X | X | X | X |
Citric Acid Monohydrate | Very Soluble | Freely Soluble | Sparingly Soluble | X | X | X | X |
Clarithromycin | Practically Insoluble | X | X | X | Slightly Soluble | Soluble | Soluble |
Clemastine Fumarate | Very Slightly Soluble | Sparingly Soluble | X | X | Slightly Soluble | X | X |
Clindamycin Hydrochloride | Very Soluble | Slightly Soluble | X | X | X | X | X |
Clindamycin Palmitate Hydrochloride | Very Soluble | Slightly Soluble | X | X | X | X | X |
Clindamycin Phosphate | Freely Soluble | Very Slightly Soluble | X | X | X | X | Practically Insoluble |
Clioquinol | Practically Insoluble | Very Slightly Soluble | X | X | X | X | X |
Clobazam | Slightly Soluble | Sparingly Soluble | X | X | X | X | Freely Soluble |
Clobetasol Propionate | Sparingly Soluble | Sparingly Soluble | X | X | X | Freely Soluble | X |
Clobetasone Butyrate | Practically Insoluble | Slightly Soluble | X | X | X | Freely Soluble | Freely Soluble |
Clofazimine | Practically Insoluble | Slightly Soluble | Very Slightly Soluble | Soluble | X | X | X |
Clomifene Citrate | Slightly Soluble | Sparingly Soluble | Practically Insoluble | X | X | X | X |
Clomipramine Hydrochloride | Freely Soluble | Soluble | X | X | X | X | Freely Soluble |
Clonazepam | Practically Insoluble | Slightly Soluble | X | X | Slightly Soluble | X | X |
Clonidine Hydrochloride | Freely Soluble | Freely Soluble | Practically Insoluble | Slightly Soluble | X | X | X |
Clopidogrel Bisulphate | X | X | Practically Insoluble | X | Freely Soluble | X | X |
Cloprostenol Sodium | Freely Soluble | Freely Soluble | X | X | Freely Soluble | Practically Insoluble | X |
Closantel Sodium Dihydrate | Very Slightly Soluble | Freely Soluble | X | X | Soluble | X | X |
Clotrimazole | Practically Insoluble | Freely Soluble | X | X | Freely Soluble | Freely Soluble | X |
Cloxacillin Benzathine | Slightly Soluble | Slightly Soluble | X | X | Freely Soluble | X | Soluble |
Cloxacillin Sodium | Freely Soluble | Soluble | X | Slightly Soluble | Freely Soluble | X | X |
Clozapine | Practically Insoluble | Soluble | X | X | X | X | Freely Soluble |
Codeine Phosphate | Freely Soluble | Slightly Soluble | Practically Insoluble | Sparingly Soluble | X | X | X |
Colchicine | Freely Soluble | Freely Soluble | Slightly Soluble | Freely Soluble | X | X | X |
Colistimethate Sodium | Very Soluble | Slightly Soluble | X | X | X | Practically Insoluble | X |
Colistin Sulphate | Freely Soluble | Slightly Soluble | X | X | X | Practically Insoluble | X |
Cortisone Acetate | Practically Insoluble | Slightly Soluble | Slightly Soluble | Soluble | X | Sparingly Soluble | X |
Cresol | Practically Insoluble | Soluble | Soluble | Soluble | X | X | X |
Cresol with Soap Solution | Soluble | Soluble | X | X | X | X | X |
Croscarmellose Sodium | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Crospovidone | X | Practically Insoluble | Practically Insoluble | X | X | X | X |
Crotamiton | Slightly Soluble | Soluble | X | X | X | X | X |
Cyanocobalamin | Sparingly Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Cyclizine Hydrochloride | Slightly Soluble | Slightly Soluble | Practically Insoluble | X | X | X | X |
Cyclobenzaprine Hydrochloride | Soluble | X | X | X | Soluble | X | X |
Alfacyclodextrin | Freely Soluble | X | Practically Insoluble | X | X | X | Practically Insoluble |
Betacyclodextrin | Sparingly Soluble | Practically Insoluble | X | X | X | X | Practically Insoluble |
Cyclopentolate Hydrochloride | Very Soluble | Freely Soluble | X | X | X | X | X |
Cyclophosphamide | Soluble | Freely Soluble | Slightly Soluble | X | X | X | X |
Cycloserine | Freely Soluble | Very Slightly Soluble | X | Practically Insoluble | X | X | X |
Cyclosporine | Practically Insoluble | Soluble | Soluble | Soluble | Soluble | Soluble | X |
Cyproheptadine Hydrochloride | Slightly Soluble | Sparingly Soluble | Practically Insoluble | Soluble | Freely Soluble | X | X |
Cyproterone Acetate | Practically Insoluble | Sparingly Soluble | X | X | Soluble | Freely Soluble | Very Soluble |
Cytarabine | Freely Soluble | Soluble | X | X | X | X | Soluble |
Dacarbazine | Slightly Soluble | Slightly Soluble | X | X | X | X | Practically Insoluble |
Daclatasvir Dihydrochloride | X | X | X | X | Soluble | X | X |
Dalteparin Sodium | Freely Soluble | X | X | X | X | X | X |
Danazol | Practically Insoluble | Sparingly Soluble | X | Freely Soluble | X | Soluble | X |
Dapoxetine Hydrochloride | Practically Insoluble | Practically Insoluble | X | X | Soluble | X | Soluble |
Dapsone | Slightly Soluble | Sparingly Soluble | X | X | X | Freely Soluble | X |
Darifenacin Hydrobromide | X | X | X | X | X | X | Soluble |
Darunavir Ethanolate | X | X | X | X | Soluble | X | X |
Daunorubicin Hydrochloride | Freely Soluble | Slightly Soluble | X | X | Freely Soluble | Practically Insoluble | X |
Decoquinate | Practically Insoluble | Practically Insoluble | Very Slightly Soluble | Very Slightly Soluble | X | X | X |
Dehydroacetic Acid | Very Slightly Soluble | Sparingly Soluble | X | X | X | Freely Soluble | X |
Dehydroemetine Hydrochloride | Soluble | Slightly Soluble | X | X | X | X | X |
Deltamethrin | Practically Insoluble | Soluble | X | X | X | Soluble | X |
Dequalinium Chloride | Slightly Soluble | X | X | X | X | X | X |
Desferrioxamine Mesylate | Freely Soluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | Slightly Soluble | X | X |
Desmopresin. | Soluble | Soluble | X | X | X | X | X |
Desoxycortone Acetate | Practically Insoluble | Sparingly Soluble | X | Freely Soluble | X | Soluble | X |
Dexamethasone | Practically Insoluble | Sparingly Soluble | Very Slightly Soluble | Slightly Soluble | Sparingly Soluble | Sparingly Soluble | X |
Dexamethasone Sodium Phosphate | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Dexchlorpheniramine Maleate | Very Soluble | Freely Soluble | X | X | Freely Soluble | X | Freely Soluble |
Dexlansoprazole | Soluble | X | X | X | Soluble | X | X |
Dextrin | Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Dextromethorphan Hydrobromide | Sparingly Soluble | Freely Soluble | Practically Insoluble | X | X | X | X |
Dextropropoxyphene Hydrochloride | Very Soluble | Freely Soluble | Practically Insoluble | X | X | X | X |
Dextropropoxyphene Napsilate. | Practically Insoluble | Soluble | X | Freely Soluble | X | X | X |
Dextros | Freely Soluble | Sparingly Soluble | X | X | X | X | X |
Diacerein | Practically Insoluble | X | X | Practically Insoluble | Practically Insoluble | X | X |
Diazepam | Very Slightly Soluble | Freely Soluble | X | Freely Soluble | X | X | X |
Diazoxide | Practically Insoluble | Slightly Soluble | Practically Insoluble | X | X | X | X |
Dichlofenthion | X | Soluble | X | X | X | X | Soluble |
Diclazuril | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X | X | X |
Diclofenac Diethylamine | Sparingly Soluble | Freely Soluble | X | X | Freely Soluble | X | X |
Diclofenac Sodium | Sparingly Soluble | Soluble | Practically Insoluble | Practically Insoluble | Freely Soluble | X | X |
Dichlorophen | Practically Insoluble | Freely Soluble | Very soluble | X | X | X | X |
Dicloxacillin Sodium | Freely Soluble | Soluble | X | X | Soluble | X | X |
Dicyclomine Hydrochloride | Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Didanosine | Soluble | X | X | X | X | X | X |
Dienoestrol | Practically Insoluble | Freely Soluble | Soluble | Slightly Soluble | X | Freely Soluble | X |
Dienogest | Practically Insoluble | X | X | X | X | X | Slightly Soluble |
Diethanolamine | Very Soluble | X | X | X | X | X | X |
Diethylcarbamazine Citrate | Very Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Diethylene Glycol Monoethyl Ether | Soluble | Soluble | X | X | X | Soluble | X |
Diethyl Phenyl Acetamide | Soluble | Soluble | Soluble | X | X | X | X |
Diethyl Phthalate | Practically Insoluble | Soluble | Soluble | X | X | X | X |
Diethyltoluamide | Practically Insoluble | Soluble | Soluble | Soluble | X | X | X |
Digitoxin | Practically Insoluble | Slightly Soluble | Slightly Soluble | Sparingly Soluble | Slightly Soluble | X | X |
Digoxin | Practically Insoluble | Slightly Soluble | X | X | Freely Soluble | X | Freely Soluble |
Dihydroergocristine Mesylate | Soluble | X | X | X | X | X | X |
Dihydroergotamine Mesylate | Slightly Soluble | Slightly Soluble | X | Slightly Soluble | X | X | X |
Dihydrostreptomycin Sulphate | Freely Soluble | Practically Insoluble | X | X | X | Practically Insoluble | Practically Insoluble |
Diiodohydroxyquinoline | Practically Insoluble | Sparingly Soluble | Sparingly Soluble | X | X | X | X |
Diloxanide Furoate | Very Slightly Soluble | Slightly Soluble | Slightly Soluble | Freely Soluble | X | X | X |
Diltiazem Hydrochloride | Freely Soluble | Sparingly Soluble | Practically Insoluble | Freely Soluble | Freely Soluble | X | X |
Dimercaprol | Soluble | Soluble | X | X | Soluble | X | X |
Dimethicone Activated | Practically Insoluble | Very Slightly Soluble | X | Soluble | Practically Insoluble | Soluble | X |
Dimetridazole | Slightly Soluble | Sparingly Soluble | Slightly Soluble | X | X | X | Freely Soluble |
Dinitolmide | Practically Insoluble | Slightly Soluble | Slightly Soluble | X | X | Soluble | Slightly Soluble |
Dinoprostone | Practically Insoluble | Freely Soluble | X | X | Very Soluble | X | X |
Diphenhydramine Hydrochloride | Very Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Diphenoxylate Hydrochloride | Very Slightly Soluble | Sparingly Soluble | Practically Insoluble | X | X | X | Freely Soluble |
Dipivefrine Hydrochloride | Freely Soluble | Freely Soluble | X | X | Very Soluble | X | Freely Soluble |
Dipyridamole | Practically Insoluble | Soluble | X | X | X | Freely Soluble | X |
Disodium Edetate | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Disopyramide | Slightly Soluble | Soluble | X | X | X | X | Freely Soluble |
Disulfiram | Practically Insoluble | Sparingly Soluble | Soluble | Soluble | X | Soluble | Freely Soluble |
Dithranol | Practically Insoluble | Slightly Soluble | Slightly Soluble | Soluble | X | X | X |
Divalproex Sodium | X | X | Freely Soluble | Very Soluble | Freely Soluble | Soluble | X |
Dobutamine Hydrochloride | Sparingly Soluble | Sparingly Soluble | X | X | Soluble | X | X |
Docetaxel Trihydrate | Practically Insoluble | Soluble | X | Soluble | Soluble | X | X |
Docusate Sodium | Very Slightly Soluble | Soluble | X | X | X | Soluble | X |
Domperidone | Practically Insoluble | Slightly Soluble | X | X | Slightly Soluble | X | X |
Domperidone Maleate | Very Slightly Soluble | Slightly Soluble | X | X | Slightly Soluble | X | X |
Donepezil Hydrochloride | Soluble | Slightly Soluble | X | Freely Soluble | X | X | X |
Dopamine Hydrochloride | Freely Soluble | Soluble | X | X | X | Sparingly Soluble | Sparingly Soluble |
Dorzolamide Hydrochloride | Soluble | X | X | X | Slightly Soluble | X | X |
Dothiepin Hydrochloride | Freely Soluble | Freely Soluble | Freely Soluble | Freely Soluble | X | X | X |
Doxapram Hydrochloride | Soluble | Soluble | X | X | X | X | Soluble |
Doxepin Hydrochloride | Freely Soluble | Freely Soluble | X | Freely Soluble | X | X | X |
Doxofylline | Soluble | X | Soluble | Soluble | Soluble | Soluble | X |
Doxorubicin Hydrochloride | Soluble | X | Practically Insoluble | Practically Insoluble | Slightly Soluble | X | X |
Doxycycline Hydrochloride | Freely Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Drospirenone | Practically Insoluble | X | X | X | Soluble | Soluble | Freely Soluble |
Drotaverine Hydrochloride | Sparingly Soluble | Soluble | X | Freely Soluble | X | X | X |
Duloxetine Hydrochloride | Sparingly Soluble | X | X | X | Freely Soluble | X | X |
Dutasteride | X | X | X | X | Soluble | X | X |
Dydrogesterone | Practically Insoluble | Sparingly Soluble | Slightly Soluble | Freely Soluble | Sparingly Soluble | Soluble | X |
Ebastine | Practically Insoluble | X | X | X | Sparingly Soluble | X | Very Soluble |
Eberconazole Nitrate | Very Slightly Soluble | X | X | X | Freely Soluble | X | X |
Econazole Nitrate | Very Slightly Soluble | Slightly Soluble | Practically Insoluble | X | Soluble | X | Sparingly Soluble |
Efavirenz | X | X | X | X | Freely Soluble | X | Freely Soluble |
Eletriptan Hydrobromide | X | X | X | X | X | X | X |
Emtricitabine | Soluble | X | X | X | Sparingly Soluble | X | X |
Emulsifying Wax | Practically Insoluble | Slightly Soluble | X | X | X | X | X |
Enalapril Maleate | Sparingly Soluble | Soluble | X | X | Freely Soluble | X | X |
Enoxaparin Sodium | Practically Insoluble | Soluble | X | X | X | X | Sparingly Soluble |
Enrofloxacin | Practically Insoluble | X | X | X | Slightly Soluble | X | X |
Entacapone | Practically Insoluble | Slightly Soluble | Slightly Soluble | Slightly Soluble | Slightly Soluble | Sparingly Soluble | X |
Entecavir | X | X | X | X | X | X | X |
Ephedrine Hydrochloride | Freely Soluble | Soluble | Soluble | X | X | X | X |
Epinastine Hydrochloride | Freely Soluble | X | X | X | Freely Soluble | X | Sparingly Soluble |
Eplerenone | Very Slightly Soluble | X | X | Soluble | X | X | Soluble |
Ergocalciferol | Practically Insoluble | Freely Soluble | Freely Soluble | Freely Soluble | X | X | X |
Ergometrine Maleate | Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Ergotamine Tartrate | Soluble | Slightly Soluble | Practically Insoluble | Slightly Soluble | X | X | X |
Erlotinib hydrochloride | X | X | X | X | Slightly Soluble | Practically Insoluble | X |
Erythromycin | Slightly Soluble | Freely Soluble | X | Soluble | Soluble | X | X |
Erythromycin Stearate | X | Soluble | X | Soluble | Soluble | Soluble | X |
Escitalopram Oxalate | Sparingly Soluble | Sparingly Soluble | X | X | X | X | X |
Eslicarbazepine Acetate | Practically Insoluble | X | X | X | Sparingly Soluble | X | X |
Esmolol Hydrochloride | Very Soluble | Freely Soluble | X | X | X | X | X |
Esomeprazole Magnesium | X | X | X | X | X | X | X |
Ethacrynic Acid | Very Slightly Soluble | Freely Soluble | Freely Soluble | Freely Soluble | X | X | X |
Ethambutol Hydrochloride | Freely Soluble | Freely Soluble | Slightly Soluble | Slightly Soluble | X | X | X |
Ethanol | Soluble | X | Soluble | Soluble | X | X | X |
Ethanolamine | Soluble | Soluble | Slightly Soluble | X | X | X | X |
Ether Anaesthetic | Soluble | Soluble | X | Soluble | X | X | X |
Ethinyloestradiol | Practically Insoluble | Freely Soluble | Freely Soluble | Sparingly Soluble | X | X | X |
Ethionamide | Practically Insoluble | X | Slightly Soluble | Slightly Soluble | Soluble | X | X |
Ethopabate | Very Slightly Soluble | Sparingly Soluble | Slightly Soluble | X | Soluble | X | Soluble |
Ethopropazine Hydrochloride | Slightly Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | Sparingly Soluble | X |
Ethosuximide | Freely Soluble | Very Soluble | X | X | X | X | X |
Ethylcellulose | Practically Insoluble | Freely Soluble | X | Freely Soluble | Freely Soluble | Freely Soluble | X |
Ethyl Chloride | Slightly Soluble | Soluble | Slightly Soluble | X | X | X | X |
Ethyl Oleate | Practically Insoluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Ethyl Paraben | Very Slightly Soluble | Freely Soluble | X | X | Freely Soluble | X | X |
Ethyl Vanilllin | X | Freely Soluble | Freely Soluble | Freely Soluble | X | X | X |
Ethylenediamine Hydrate | Soluble | Soluble | Slightly Soluble | Slightly Soluble | X | X | X |
Ethyloestrenol | Practically Insoluble | Freely Soluble | Freely Soluble | Freely Soluble | X | X | X |
Etidronate Disodium | Very Soluble | Freely Soluble | X | X | X | Practically Insoluble | X |
Etodolac | Practically Insoluble | Soluble | X | Soluble | X | X | X |
Etoposide | Practically Insoluble | Slightly Soluble | X | X | Sparingly Soluble | X | Slightly Soluble |
Etoricoxib | X | Sparingly Soluble | X | X | Soluble | Soluble | X |
Exemestane | Practically Insoluble | X | X | X | Soluble | X | Freely Soluble |
Ezetimibe | X | Freely Soluble | X | X | Freely Soluble | Freely Soluble | X |
Famciclovir | X | Sparingly Soluble | X | X | Freely Soluble | Freely Soluble | X |
Famotidine | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | X | Slightly Soluble | Practically Insoluble | X |
Fasudil Hydrochloride | Freely Soluble | Practically Insoluble | X | X | X | X | X |
Febantel | Practically Insoluble | Slightly Soluble | X | X | X | Soluble | X |
Felodipine | X | Freely Soluble | X | X | Freely Soluble | Freely Soluble | Freely Soluble |
Fenbendazole | Practically Insoluble | X | X | X | Very Slightly Soluble | X | X |
Fenofibrate | Practically Insoluble | Slightly Soluble | X | X | X | X | Very Soluble |
Fenspiride Hydrochloride | Soluble | X | X | X | X | X | X |
Fentanyl | Practically Insoluble | Freely Soluble | X | X | Freely Soluble | X | X |
Fentanyl Citrate | Soluble | Sparingly Soluble | X | X | Freely Soluble | X | X |
Ferrous Fumarate | Slightly Soluble | Very Slightly Soluble | X | X | X | X | X |
Ferrous Gluconate | Soluble | Practically Insoluble | X | X | X | X | X |
Ferrous Sulphate | Freely Soluble | Practically Insoluble | X | X | X | X | X |
Ferrous Sulphate Dried | Soluble | X | X | X | X | X | X |
Fesoterodine Fumarate | Freely Soluble | X | X | X | Freely Soluble | X | X |
Fexofenadine Hydrochloride | X | X | X | X | Freely Soluble | X | X |
Finasteride | Practically Insoluble | Freely Soluble | X | X | X | X | Freely Soluble |
Fingolimod Hydrochloride | X | X | X | X | Soluble | X | X |
Flavoxate Hydrochloride | Slightly Soluble | Slightly Soluble | X | X | X | X | Sparingly Soluble |
Flucloxacillin Sodium | Freely Soluble | Soluble | X | X | Freely Soluble | X | X |
Fluconazole | Slightly Soluble | X | X | X | X | X | X |
Flucytosine | Sparingly Soluble | Slightly Soluble | Practically Insoluble | X | X | X | X |
Fludarabine Phosphate | Slightly Soluble | Very Slightly Soluble | X | X | X | X | X |
Fludrocortisone Acetate | Practically Insoluble | Sparingly Soluble | Slightly Soluble | Sparingly Soluble | X | X | X |
Flumazenil | Very Slightly Soluble | X | X | X | Sparingly Soluble | X | Freely Soluble |
Flunixin Meglumine | Freely Soluble | X | X | X | Freely Soluble | Practically Insoluble | X |
Fluocinolone Acetonide | Practically Insoluble | Soluble | X | Slightly Soluble | X | Soluble | X |
Fluorescein Sodium | Freely Soluble | Sparingly Soluble | X | X | X | X | X |
Fluorometholone | Practically Insoluble | Slightly Soluble | Very Slightly Soluble | Very Slightly Soluble | X | X | X |
Fluorouracil | Sparingly Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Fluoxetine Hydrochloride | Sparingly Soluble | X | X | X | Freely Soluble | X | Sparingly Soluble |
Flupentixol Decanoate | Very Slightly Soluble | Soluble | Freely Soluble | X | X | X | X |
Fluphenazine Decanoate | Practically Insoluble | Soluble | Soluble | Soluble | X | X | X |
Fluphenazine Hydrochloride | Freely Soluble | Sparingly Soluble | Practically Insoluble | X | X | X | Sparingly Soluble |
Flurazepam Hydrochloride | Soluble | Freely Soluble | X | X | X | X | X |
Flurbiprofen | Practically Insoluble | Freely Soluble | Freely Soluble | Freely Soluble | X | X | X |
Flurbiprofen Sodium | Sparingly Soluble | Soluble | X | X | X | X | Practically Insoluble |
Flutamide | Practically Insoluble | Freely Soluble | X | X | X | Freely Soluble | X |
Fluticasone propionate | Practically Insoluble | Slightly Soluble | X | X | X | X | Sparingly Soluble |
Fluvastatin Sodium | Soluble | X | X | X | Freely Soluble | X | X |
Fluvoxamine Maleate | Sparingly Soluble | Freely Soluble | X | X | Freely Soluble | X | X |
Folic Acid | Soluble | X | X | X | X | X | X |
Fomepizole | Very Soluble | Very Soluble | X | X | X | X | X |
Formoterol Fumarate Dihydrate | Slightly Soluble | X | X | X | Soluble | X | X |
Fosinopril Sodium | Freely Soluble | Sparingly Soluble | X | X | X | X | X |
Framycetin Sulphate | Freely Soluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Frovatriptan Succinate | Slightly Soluble | X | X | X | Slightly Soluble | Practically Insoluble | X |
D-Fructose | Very Soluble | Soluble | X | X | X | X | X |
Frusemide | Practically Insoluble | Sparingly Soluble | X | X | X | Soluble | X |
Fulvestrant | Practically Insoluble | Freely Soluble | X | X | X | X | Freely Soluble |
Fumaric Acid | Slightly Soluble | Soluble | Slightly Soluble | Very Slightly Soluble | X | X | X |
Furazolidone | Very Slightly Soluble | Very Slightly Soluble | Practically Insoluble | Slightly Soluble | X | X | X |
Fusidic Acid | Practically Insoluble | Freely Soluble | Sparingly Soluble | Freely Soluble | X | X | X |
Gabapentin | Sparingly Soluble | Slightly Soluble | X | X | X | X | Practically Insoluble |
Galantamine Hydrobromide | Sparingly Soluble | Very Slightly Soluble | X | X | X | X | X |
Gallamine Triethiodide | Very Soluble | Slightly Soluble | Practically Insoluble | Very Slightly Soluble | X | X | X |
Ganciclovir | Slightly Soluble | Very Slightly Soluble | X | X | X | X | X |
Gefitinib | X | X | X | X | X | X | X |
Gelatin | Soluble | X | X | X | X | X | X |
Gemcitabine Hydrochloride | Soluble | X | X | X | Slightly Soluble | Practically Insoluble | X |
Gemfibrozil | Practically Insoluble | Freely Soluble | X | X | Freely Soluble | X | Very Soluble |
Gemifloxacin Mesylate | Sparingly Soluble | X | X | X | Practically Insoluble | X | X |
Gentamicin Sulphate | Freely Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Glibenclamide | Practically Insoluble | Slightly Soluble | Practically Insoluble | X | Slightly Soluble | X | Sparingly Soluble |
Gliclazide | X | Slightly Soluble | X | X | X | Sparingly Soluble | Freely Soluble |
Glimepiride | Practically Insoluble | X | X | X | Slightly Soluble | X | Sparingly Soluble |
Glipizide | Practically Insoluble | Practically Insoluble | X | X | X | Very Slightly Soluble | Very Slightly Soluble |
Glucosamine Sulphate Sodium Chloride | Freely Soluble | X | X | X | Sparingly Soluble | Practically Insoluble | X |
Glycerin | Soluble | Soluble | Practically Insoluble | X | X | Slightly Soluble | X |
Glyceryl Monostearate | Practically Insoluble | Soluble | Soluble | Freely Soluble | X | X | X |
Glyceryl Trinitrate Solution, Concentrated | X | X | Soluble | X | X | Soluble | X |
Glycine | Freely Soluble | Very Slightly Soluble | Practically Insoluble | X | X | X | X |
Glycopyrrolate | Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Gramicidin | Practically Insoluble | Sparingly Soluble | X | X | Soluble | X | X |
Griseofulvin | Practically Insoluble | Slightly Soluble | X | Soluble | Slightly Soluble | Soluble | X |
Guaiphenesin | Sparingly Soluble | Soluble | Slightly Soluble | Soluble | X | X | X |
Guar Gum | X | Practically Insoluble | X | X | X | X | X |
Guggul Resin | Practically Insoluble | Sparingly Soluble | X | Sparingly Soluble | Sparingly Soluble | X | X |
Gugulipid | Practically Insoluble | Soluble | X | Soluble | Soluble | X | X |
Haloperidol | Practically Insoluble | Sparingly Soluble | Slightly Soluble | Soluble | X | X | Sparingly Soluble |
Haloxon | Practically Insoluble | Freely Soluble | X | X | X | Freely Soluble | Freely Soluble |
Heparin Sodium | Soluble | X | X | X | X | X | X |
Histamine Phosphate | Freely Soluble | Slightly Soluble | X | X | X | X | X |
Homatropine Hydrobromide | Freely Soluble | Sparingly Soluble | Very Slightly Soluble | X | X | X | X |
Homatropine Methylbromide | Freely Soluble | Slightly Soluble | Practically Insoluble | X | X | X | X |
Hyaluronidase | Very Soluble | Practically Insoluble | Practically Insoluble | X | X | Practically Insoluble | X |
Hydralazine Hydrochloride | Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | Slightly Soluble | X | Practically Insoluble |
Hydrochloric Acid | Soluble | X | X | X | X | X | X |
Hydrochlorothiazide | Very Slightly Soluble | Sparingly Soluble | X | X | X | Soluble | X |
Hydrocortisone | Practically Insoluble | Sparingly Soluble | Very Slightly Soluble | Slightly Soluble | X | Sparingly Soluble | X |
Hydrocortisone Acetate | Practically Insoluble | Slightly Soluble | X | Slightly Soluble | X | X | X |
Hydrocortisone Hemisuccinate | Practically Insoluble | Freely Soluble | Practically Insoluble | X | X | Freely Soluble | X |
Hydroxocobalamin | Soluble | X | X | X | X | X | X |
Hydroxychloroquine Sulphate | Freely Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Hydroxyethylcellulose | Soluble | X | X | X | X | Practically Insoluble | X |
Hydroxyprogesterone Hexanoate | Practically Insoluble | Freely Soluble | Freely Soluble | Very Soluble | X | X | X |
Hydroxypropylcellulose | Soluble | Soluble | X | X | Soluble | Slightly Soluble | X |
Hydroxypropylmethylcellulose | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | Practically Insoluble | X |
Hydroxypropyl Methylcellulose Phthalate | Practically Insoluble | Practically Insoluble | X | X | X | Very Slightly Soluble | X |
Hydroxyurea | Freely Soluble | Soluble | X | X | X | X | X |
Hydroxyzine Hydrochloride | Freely Soluble | Freely Soluble | X | X | X | Very Slightly Soluble | X |
Hyoscine Butylbromide | Freely Soluble | Sparingly Soluble | X | Freely Soluble | X | X | X |
Hyoscine Hydrobromide | Freely Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Hyoscyamine Sulphate | Very Soluble | Sparingly Soluble | Practically Insoluble | X | X | X | X |
Ibudilast | X | X | X | X | Soluble | X | X |
Ibuprofen | Practically Insoluble | Freely Soluble | Freely Soluble | Freely Soluble | X | Freely Soluble | X |
Idoxuridine | Slightly Soluble | Slightly Soluble | Practically Insoluble | X | X | X | X |
Ifosfamide | Soluble | X | X | X | X | X | Freely Soluble |
Iloperidone | Practically Insoluble | X | X | Freely Soluble | X | Sparingly Soluble | X |
Imatinib Mesylate | Soluble | X | X | X | X | X | X |
Imidurea | Soluble | X | X | X | X | X | X |
Imipenem | Sparingly Soluble | X | X | X | Slightly Soluble | X | X |
Imipramine Hydrochloride | Freely Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Indapamide | Practically Insoluble | Soluble | Very Slightly Soluble | X | X | X | X |
Indinavir Sulphate | Freely Soluble | X | X | X | Soluble | X | X |
Indomethacin | Practically Insoluble | Sparingly Soluble | Sparingly Soluble | Soluble | X | X | X |
myo-Inositol | Very Soluble | Practically Insoluble | X | X | X | X | X |
Insulin | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Insulin Aspart | X | Practically Insoluble | X | X | Practically Insoluble | X | X |
Insulin Glargine | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Insulin, Human | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Insulin Lispro | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Iodine | Very Slightly Soluble | Soluble | X | Soluble | X | X | X |
Iopanoic Acid | Practically Insoluble | Soluble | X | X | Soluble | X | X |
Ipratropium Bromide | Soluble | Slightly Soluble | X | X | Freely Soluble | X | X |
Irbesartan Hydrochloride | Practically Insoluble | X | X | X | Sparingly Soluble | X | Slightly Soluble |
Irinotecan Hydrochloride Trihydrate | Slightly Soluble | Slightly Soluble | X | X | X | X | X |
Iron and Ammonium Citrate | Very Soluble | Practically Insoluble | X | X | X | X | X |
Isoflupredone Acetate | Practically Insoluble | Sparingly Soluble | Practically Insoluble | X | X | Sparingly Soluble | Practically Insoluble |
Isoflurane | Practically Insoluble | Soluble | X | X | X | X | X |
Isoniazid | Freely Soluble | Sparingly Soluble | Very Slightly Soluble | Slightly Soluble | X | X | X |
Isoprenaline Hydrochloride | Freely Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Isoprenaline Sulphate | Freely Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Isopropyl Alcohol | Soluble | X | Soluble | Soluble | X | X | X |
Isopropyl Myristate | Practically Insoluble | Soluble | X | X | X | X | Soluble |
Isopropyl Palmitate | Practically Insoluble | Soluble | X | X | X | X | Soluble |
Isosorbide Dinitrate, Diluted | Very Slightly Soluble | Sparingly Soluble | X | Freely Soluble | X | Very Soluble | X |
Isosorbide, Mononitrate, Diluted | X | Soluble | X | X | X | X | X |
Isotretenoin | Practically Insoluble | Slightly Soluble | X | X | X | X | Soluble |
Isoxsuprine Hydrochloride | Slightly Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Ivermectin | Practically Insoluble | Soluble | X | X | X | X | Freely Soluble |
Kanamycin Acid Sulphate | Freely Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Kanamycin Sulphate | Freely Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Heavy Kaolin | Practically Insoluble | X | X | X | X | X | X |
Light Kaolin | Practically Insoluble | X | X | X | X | X | X |
Ketamine Hydrochloride | Freely Soluble | Soluble | Practically Insoluble | Sparingly Soluble | X | X | X |
Ketoconazole | Practically Insoluble | X | X | Soluble | Soluble | X | X |
Ketoprofen | Practically Insoluble | Freely Soluble | Freely Soluble | Soluble | X | X | X |
Ketorolac Tromethamine | Freely Soluble | Slightly Soluble | X | X | Freely Soluble | X | Practically Insoluble |
Ketotifen Fumarate | Sparingly Soluble | X | X | X | Slightly Soluble | X | X |
Labetalol Hydorchloride | Sparingly Soluble | Sparingly Soluble | X | Practically Insoluble | X | X | X |
Lacidipine | Practically Insoluble | Sparingly Soluble | X | X | X | Freely Soluble | X |
Lactic acid. | Soluble | Soluble | Soluble | X | X | X | X |
Lactose | Soluble | Practically Insoluble | X | X | X | X | X |
Lactulose | Freely Soluble | X | X | X | Sparingly Soluble | X | X |
Lamivudine | Soluble | X | X | X | Sparingly Soluble | X | X |
Lamotrigine | Slightly Soluble | Slightly Soluble | X | Practically Insoluble | X | X | X |
Lansoprazole | Practically Insoluble | X | X | X | X | X | X |
Lapatinib Ditosylate | Practically Insoluble | X | X | X | X | X | X |
Latanoprost | Practically Insoluble | Freely Soluble | X | X | Freely Soluble | Freely Soluble | X |
Lecithin | Slightly Soluble | Sparingly Soluble | X | X | X | X | X |
Leflunomide | Practically Insoluble | X | X | X | Freely Soluble | X | Sparingly Soluble |
Letrozole | Practically Insoluble | X | X | X | Sparingly Soluble | X | X |
Levamisole Hydrochloride | Freely Soluble | Soluble | Practically Insoluble | X | X | X | Slightly Soluble |
Levetiracetam | Very Soluble | X | X | X | X | X | X |
Levocetirizine Hydrochloride | Freely Soluble | Soluble | X | X | Soluble | X | X |
Levodopa | Slightly Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Levodropropizine | Soluble | Soluble | X | X | Freely Soluble | X | X |
Levofloxacin Hemihydrate | X | X | X | Sparingly Soluble | Slightly Soluble | X | X |
Levonorgestrel | Practically Insoluble | Slightly Soluble | Slightly Soluble | Sparingly Soluble | X | Slightly Soluble | Sparingly Soluble |
Levosalbutamol Hydrochloride | Soluble | X | X | X | Soluble | X | X |
Levosalbutamol Sulphate | Freely Soluble | Very Slightly Soluble | X | Very Slightly Soluble | X | X | X |
Lignocaine | Practically Insoluble | Very Soluble | Freely Soluble | Very Soluble | X | X | X |
Lignocaine Hydrochloride | Very Soluble | X | Practically Insoluble | Freely Soluble | X | X | X |
Lincomycin Hydrochloride | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | Very Slightly Soluble | X |
Linezolid | X | X | X | Soluble | Slightly Soluble | X | X |
Lindane | Practically Insoluble | Soluble | Freely Soluble | X | X | Freely Soluble | X |
Lisinopril | Soluble | Very Slightly Soluble | X | X | X | X | X |
Lithium Antimony Thiomalate | Soluble | Slightly Soluble | Slightly Soluble | X | X | X | X |
Lithium Carbonate | Slightly Soluble | Practically Insoluble | X | X | X | X | X |
Lomustine | Practically Insoluble | X | X | Freely Soluble | X | Freely Soluble | Freely Soluble |
Loperamide Hydrochloride | Slightly Soluble | Soluble | X | X | Freely Soluble | X | X |
Lopinavir | Practically Insoluble | X | X | X | Freely Soluble | X | Freely Soluble |
Lorazepam | Practically Insoluble | Sparingly Soluble | X | X | X | X | Sparingly Soluble |
Lorcaserin Hydrochloride Hemihydrate | X | X | X | Soluble | Soluble | X | X |
Losartan Potassium | Freely Soluble | X | X | X | X | X | X |
Lubiprostone | X | X | X | X | X | Soluble | X |
Lynoestrenol | Practically Insoluble | Soluble | Soluble | Freely Soluble | X | Soluble | X |
Magaldrate | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Heavy Magnesium Carbonate | Practically Insoluble | X | X | X | X | X | X |
Light Magnesium Carbonate | Practically Insoluble | X | X | X | X | X | X |
Magnesium Chloride | Very Soluble | Freely Soluble | X | X | X | X | X |
Magnesium hydroxide | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Magnesium Hypophosphite | Freely Soluble | Practically Insoluble | X | X | X | X | X |
Heavy Magnesium Oxide | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Light Magnesium Oxide | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Magnesium Stearate | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Magnesium Sulphate | Freely Soluble | Practically Insoluble | X | X | X | X | X |
Magnesium Trisilicate | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Maleic Acid | Freely Soluble | Freely Soluble | X | X | X | X | X |
Malic Acid | Freely Soluble | Freely Soluble | X | X | X | Sparingly Soluble | X |
Malt Extract | Soluble | X | X | X | X | X | X |
Maltitol | Very Soluble | Practically Insoluble | X | X | X | X | X |
Liquid Maltitol | Soluble | X | X | X | X | X | X |
Maltodextrin | Freely Soluble | X | X | X | X | X | X |
Mannitol | Freely Soluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Marbofloxacin | Slightly Soluble | Very Slightly Soluble | X | X | X | X | X |
Mebendazole | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X | Practically Insoluble |
Mebeverine Hydrochloride | Very Soluble | Freely Soluble | Practically Insoluble | X | X | X | X |
Meclizine Hydrochloride | Slightly Soluble | Soluble | Practically Insoluble | Soluble | X | X | Soluble |
Meclofenamic Acid | Practically Insoluble | Slightly Soluble | Sparingly Soluble | X | X | X | Slightly Soluble |
Medroxyprogesterone Acetate | Practically Insoluble | Sparingly Soluble | Slightly Soluble | Freely Soluble | Sparingly Soluble | Soluble | X |
Mefenamic Acid | Practically Insoluble | Slightly Soluble | Sparingly Soluble | Slightly Soluble | X | X | X |
Mefloquine Hydrochloride | Slightly Soluble | Soluble | X | X | X | X | X |
Megestrol Acetate | Practically Insoluble | Sparingly Soluble | Slightly Soluble | Very Soluble | X | X | X |
Meloxicam | Practically Insoluble | Very Slightly Soluble | X | X | X | X | X |
Melphalan | Practically Insoluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | Slightly Soluble | X | X |
Memantine Hydrochloride | Slightly Soluble | X | X | X | X | X | X |
Menthol | Slightly Soluble | Very Soluble | Very Soluble | X | X | X | X |
Mephentermine Sulphate | Soluble | Very Slightly Soluble | X | X | X | X | X |
Mepyramine Maleate | Very Soluble | Freely Soluble | Very Slightly Soluble | Freely Soluble | X | X | X |
Mercaptopurine | Practically Insoluble | Slightly Soluble | Practically Insoluble | X | X | X | X |
Meropenem | Sparingly Soluble | Very Slightly Soluble | Practically Insoluble | X | X | Practically Insoluble | X |
Mesalazine | Very Slightly Soluble | Practically Insoluble | X | X | X | X | X |
Mesna | Freely Soluble | Soluble | X | X | X | X | X |
Mestranol | Practically Insoluble | Sparingly Soluble | Soluble | Freely Soluble | Slightly Soluble | X | X |
Metadoxine | Freely Soluble | X | Practically Insoluble | Practically Insoluble | Soluble | X | X |
Metformin Hydrochloride | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | Practically Insoluble |
Methadone Hydrochloride | Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Methocarbamol | Sparingly Soluble | Soluble | X | Sparingly Soluble | X | X | X |
Methotrexate | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X | Practically Insoluble |
Methoxamine Hydrochloride | Freely Soluble | Soluble | Very Slightly Soluble | Very Slightly Soluble | X | X | X |
Methylcellulose | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | Practically Insoluble | X |
Methylcobalamin | Sparingly Soluble | Slightly Soluble | X | X | X | X | X |
Methyldopa | Sparingly Soluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Methylergometrine Maleate | Slightly Soluble | Soluble | Very Slightly Soluble | Very Slightly Soluble | X | X | X |
Methylparaben | Very Slightly Soluble | Freely Soluble | Freely Soluble | X | Freely Soluble | X | X |
Methylphenidate Hydrochloride | Freely Soluble | Soluble | X | Slightly Soluble | Freely Soluble | Slightly Soluble | X |
Methyl prednisolone | Practically Insoluble | Sparingly Soluble | Very Slightly Soluble | Slightly Soluble | X | Slightly Soluble | X |
Methyl Prednisolone Acetate | Practically Insoluble | Slightly Soluble | Very Slightly Soluble | X | X | X | X |
Methyl Salicylate | Very Slightly Soluble | Soluble | X | Soluble | X | X | X |
Metoclopramide Hydrochloride | Very Soluble | Freely Soluble | Practically Insoluble | X | X | X | Sparingly Soluble |
Metolazone | Very Slightly Soluble | X | X | X | Sparingly Soluble | Slightly Soluble | Very Slightly Soluble |
Metoprolol Succinate | Freely Soluble | Sparingly Soluble | X | X | Soluble | X | X |
Metoprolol Tartrate | Very Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | Slightly Soluble | Freely Soluble |
Metronidazole | Slightly Soluble | Slightly Soluble | Very Slightly Soluble | X | X | Slightly Soluble | Slightly Soluble |
Metronidazole Benzoate | Practically Insoluble | Slightly Soluble | Slightly Soluble | Freely Soluble | X | Soluble | Freely Soluble |
Mexiletine Hydrochloride | Freely Soluble | X | Practically Insoluble | X | Freely Soluble | X | Sparingly Soluble |
Mianserin Hydrochloride | Sparingly Soluble | Slightly Soluble | X | Soluble | X | X | Soluble |
Miconazole | Very Slightly Soluble | X | Soluble | X | Freely Soluble | X | X |
Miconazole Nitrate | Very Slightly Soluble | Slightly Soluble | Very Slightly Soluble | Slightly Soluble | Sparingly Soluble | X | X |
Microcrystalline Cellulose | Practically Insoluble | Practically Insoluble | X | X | X | Practically Insoluble | X |
Microcrystalline Wax | Practically Insoluble | Sparingly Soluble | Soluble | Soluble | X | X | X |
Midazolam | Practically Insoluble | Freely Soluble | X | X | Soluble | Freely Soluble | X |
Mifepristone | Practically Insoluble | X | X | X | Freely Soluble | X | Freely Soluble |
Minoxidil | Slightly Soluble | Practically Insoluble | Very Slightly Soluble | Practically Insoluble | Soluble | X | X |
Mirtazipine | Practically Insoluble | Freely Soluble | X | X | X | X | X |
Misoprostol | Soluble | Soluble | X | X | X | Sparingly Soluble | X |
Mitiglinide Calcium Dihydrate | Practically Insoluble | X | X | X | Soluble | X | X |
Mitomycin | Slightly Soluble | X | X | X | Sparingly Soluble | Slightly Soluble | Freely Soluble |
Moexipril Hydrochloride | Soluble | X | X | X | X | X | X |
Mometasone Furoate | Practically Insoluble | Slightly Soluble | X | X | X | Soluble | Soluble |
Monosulfiram | Practically Insoluble | X | X | X | X | X | X |
Monothioglycerol | Freely Soluble | Soluble | Practically Insoluble | X | X | X | X |
Montelukast Sodium | Freely Soluble | Freely Soluble | X | X | Freely Soluble | Practically Insoluble | X |
Morphine Sulphate | Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Mosapride Citrate Dihydrate | Practically Insoluble | X | X | X | Sparingly Soluble | X | Soluble |
Moxidectin | Practically Insoluble | Very Soluble | X | X | X | X | X |
Moxifloxacin Hydrochloride | Sparingly Soluble | Slightly Soluble | X | X | X | Practically Insoluble | X |
Mupirocin | Slightly Soluble | Freely Soluble | X | X | X | Freely Soluble | Slightly Soluble |
Mustine Hydrochloride | Very Soluble | X | X | X | X | X | X |
Mycophenolate Mofetil | Practically Insoluble | Sparingly Soluble | X | X | X | Freely Soluble | X |
Myristic Acid | Practically Insoluble | X | X | X | X | X | X |
Nabumetone | Practically Insoluble | X | X | X | Slightly Soluble | Freely Soluble | X |
Nadifloxacin | X | X | X | X | X | X | X |
Nalidixic Acid | Practically Insoluble | Slightly Soluble | Very Slightly Soluble | X | X | Slightly Soluble | Soluble |
Nalorphine Hydrochloride | Freely Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Naloxone Hydrochloride | Freely Soluble | Soluble | X | X | X | X | X |
Naltrexone Hydrochloride | Freely Soluble | Slightly Soluble | X | X | X | X | Practically Insoluble |
Nandrolone Decanoate | Practically Insoluble | Freely Soluble | Freely Soluble | Freely Soluble | Freely Soluble | X | X |
Nandrolone Laurate | Practically Insoluble | Freely Soluble | Freely Soluble | X | X | X | Freely Soluble |
Nandrolone Phenylpropionate | Practically Insoluble | Soluble | X | X | X | X | X |
Naphazoline Nitrate | Practically Insoluble | Soluble | X | X | X | X | X |
Naproxcinod | X | X | X | X | Soluble | X | X |
Naproxen | Practically Insoluble | Soluble | X | X | Soluble | X | X |
Natamycin | Sparingly Soluble | Very Soluble | Very Soluble | X | X | X | X |
Nebivolol Hydrochloride | X | X | X | X | Slightly Soluble | X | X |
Nelfinavir Mesylate | X | X | X | X | Soluble | X | X |
Neomycin Sulphate | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Neostigmine Bromide | Very Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Neostigmine Methylsulphate | Very Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Neotame | Soluble | Very Soluble | X | X | X | X | X |
Netilmicin Sulphate | Very Soluble | Practically Insoluble | X | X | X | Practically Insoluble | X |
Nevirapine | X | X | X | X | X | X | Sparingly Soluble |
Nicardipine Hydrochloride | Slightly Soluble | X | X | X | Slightly Soluble | X | X |
Niclosamide | Practically Insoluble | Slightly Soluble | X | X | X | Sparingly Soluble | X |
Nicorandil | Sparingly Soluble | X | X | Sparingly Soluble | Freely Soluble | Freely Soluble | Soluble |
Nicotinamide | Freely Soluble | Freely Soluble | Slightly Soluble | Slightly Soluble | X | X | X |
Nicotinic Acid | Soluble | Soluble | Slightly Soluble | Slightly Soluble | X | X | X |
Nicoumalone | Practically Insoluble | Slightly Soluble | Practically Insoluble | Slightly Soluble | X | X | X |
Nifedipine | Practically Insoluble | Sparingly Soluble | X | Freely Soluble | X | Freely Soluble | X |
Nikethamide | Soluble | Soluble | Soluble | Soluble | X | X | X |
Nitrazepam | Practically Insoluble | Slightly Soluble | Slightly Soluble | Sparingly Soluble | X | X | X |
Nitrofurantoin | Very Slightly Soluble | Very Slightly Soluble | X | X | X | X | X |
Nitrofurazone | Very Slightly Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Nitrous Oxide | X | Freely Soluble | Soluble | X | X | X | X |
Nitroxynil | Practically Insoluble | Slightly Soluble | Sparingly Soluble | X | X | X | X |
Noradrenaline Bitartrate | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Norethisterone | Practically Insoluble | Slightly Soluble | X | Soluble | X | X | X |
Norfloxacin | Very Slightly Soluble | Slightly Soluble | Practically Insoluble | Sparingly Soluble | Very Slightly Soluble | Slightly Soluble | X |
Norgestimate | Practically Insoluble | X | X | X | X | Soluble | X |
Norgestrel | Practically Insoluble | Sparingly Soluble | X | Freely Soluble | X | X | Freely Soluble |
Nortriptyline Hydrochloride | Sparingly Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | Sparingly Soluble | X | X |
Noscapine | Practically Insoluble | Slightly Soluble | Slightly Soluble | Freely Soluble | X | Soluble | X |
Novobiocin Sodium | Freely Soluble | Freely Soluble | X | X | Freely Soluble | X | X |
Nystatin | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | Slightly Soluble | X | X |
Octyldodecanol | Practically Insoluble | Soluble | X | X | X | X | X |
Oestradiol Benzoate | Practically Insoluble | Slightly Soluble | X | X | X | Sparingly Soluble | X |
Ofloxacin | Slightly Soluble | X | X | X | Slightly Soluble | X | Slightly Soluble |
Olanzapine | Practically Insoluble | X | X | X | X | X | Freely Soluble |
Oleic Acid | Practically Insoluble | Soluble | Soluble | Soluble | X | X | Soluble |
Olmesartan Medoxomil | Practically Insoluble | Slightly Soluble | X | X | X | X | X |
Olopatadine Hydrochloride | Very Slightly Soluble | Sparingly Soluble | X | Sparingly Soluble | Sparingly Soluble | X | Soluble |
Omeprazole | Very Slightly Soluble | Freely Soluble | X | Freely Soluble | Freely Soluble | X | Freely Soluble |
Ondansetron | Sparingly Soluble | X | X | X | X | X | X |
Ondansetron Hydrochloride | Sparingly Soluble | Sparingly Soluble | X | X | Soluble | X | Sparingly Soluble |
Ormeloxifene Hydrochloride | Very Slightly Soluble | Sparingly Soluble | X | Soluble | Soluble | X | X |
Ornidazole | X | X | X | Soluble | Soluble | X | X |
Orphenadrine Citrate | Sparingly Soluble | Slightly Soluble | X | X | X | X | X |
Oseltamivir Phosphate | Soluble | X | X | X | X | X | X |
Oxacillin Sodium | Freely Soluble | X | X | X | Soluble | X | Practically Insoluble |
Oxaliplatin | Slightly Soluble | Practically Insoluble | X | X | Very Slightly Soluble | X | X |
Oxazepam | Practically Insoluble | Slightly Soluble | Very Slightly Soluble | Slightly Soluble | X | X | X |
Oxcarbazepine | Practically Insoluble | X | X | Sparingly Soluble | X | X | X |
Oxfendazole | Practically Insoluble | X | Slightly Soluble | X | Slightly Soluble | Slightly Soluble | Slightly Soluble |
Oxprenolol Hydrochloride | Very Soluble | Freely Soluble | Practically Insoluble | Soluble | X | X | X |
Oxybutynin Hydrochloride | Freely Soluble | Freely Soluble | X | X | X | Soluble | X |
Oxyclozanide | Very Slightly Soluble | Soluble | X | X | X | Freely Soluble | Slightly Soluble |
Oxymetazoline Hydrochloride | Freely Soluble | Freely Soluble | X | X | X | X | X |
Oxytetracycline | Very Slightly Soluble | Sparingly Soluble | X | X | X | X | X |
Oxytetracycline Hydrochloride | Freely Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Oxytocin | Soluble | X | X | X | X | X | X |
Ozagrel Hydrochloride | Freely Soluble | Very Slightly Soluble | X | X | Freely Soluble | Practically Insoluble | X |
Paclitaxel | Practically Insoluble | Soluble | X | X | X | X | X |
Palmitic Acid | Practically Insoluble | Soluble | X | X | X | X | X |
Paliperidone | Practically Insoluble | X | X | X | X | X | Sparingly Soluble |
Pancretin | Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
D-Panthenol | Soluble | Soluble | Slightly Soluble | Soluble | X | X | X |
Pantoprazole | Freely Soluble | Freely Soluble | X | X | Freely Soluble | X | Practically Insoluble |
Papain | Sparingly Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Paracetamol | Sparingly Soluble | Freely Soluble | Very Slightly Soluble | X | X | Freely Soluble | Very Slightly Soluble |
Hard Paraffin | Practically Insoluble | Practically Insoluble | Soluble | Soluble | X | X | X |
Liquid Paraffin | Practically Insoluble | Practically Insoluble | Soluble | Soluble | X | X | X |
Light Liquid Paraffin | Practically Insoluble | Practically Insoluble | Soluble | Soluble | X | X | X |
White Soft Paraffin | Practically Insoluble | Practically Insoluble | Soluble | Soluble | X | X | X |
Yellow Soft Paraffin | Practically Insoluble | Practically Insoluble | Soluble | Soluble | X | X | X |
Paraldehyde | Soluble | Soluble | Soluble | Soluble | X | X | X |
Parecoxib Sodium | Soluble | X | X | X | Slightly Soluble | X | X |
Paroxetine Hydrochloride | Slightly Soluble | Sparingly Soluble | X | X | Freely Soluble | X | Sparingly Soluble |
Paroxetine Hydrochloride Hemihydrate | Slightly Soluble | Sparingly Soluble | X | X | Freely Soluble | X | X |
Pemetrexed Disodium Heptahydrate | Freely Soluble | X | Very Slightly Soluble | X | X | X | X |
Penicillamine | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Pentamidine Isethionate | Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Pentazocine | Practically Insoluble | Soluble | X | Freely Soluble | X | X | X |
Pentazocine Hydrochloride | Sparingly Soluble | Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Pentazocine Lactate | Sparingly Soluble | Sparingly Soluble | X | Sparingly Soluble | Freely Soluble | X | X |
Pentobarbitone Sodium | Very Soluble | Very Soluble | Practically Insoluble | X | X | X | X |
Pepsin | Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Perphenazine | X | Soluble | X | X | X | X | Freely Soluble |
Pethidine Hydrochloride | Very Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Petrolatum | Practically Insoluble | Practically Insoluble | Soluble | Freely Soluble | X | X | X |
Phenindione | Very Slightly Soluble | Slightly Soluble | Slightly Soluble | Freely Soluble | X | X | X |
Pheniramine Maleate | Freely Soluble | Freely Soluble | Very Slightly Soluble | Freely Soluble | X | X | X |
Phenobarbitone | Very Slightly Soluble | Soluble | Soluble | Sparingly Soluble | X | X | X |
Phenobarbitone Sodium | Freely Soluble | Soluble | Practically Insoluble | X | X | X | Practically Insoluble |
Phenol | Soluble | Very Soluble | X | X | X | X | Very Soluble |
Phenolphthalein | Practically Insoluble | Soluble | Soluble | X | X | X | X |
Phenoxyethanol | Slightly Soluble | Soluble | X | X | X | Soluble | X |
Phenoxymethylpenicillin Potassium | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Phentolamine Mesylate | Freely Soluble | Freely Soluble | X | Slightly Soluble | X | X | X |
Phenylephrine Hydrochloride | Freely Soluble | Freely Soluble | X | Practically Insoluble | X | X | X |
Phenylethyl Alcohol | Slightly Soluble | Very Soluble | Very Soluble | Very Soluble | X | X | X |
Phenylmercuric Acetate | Slightly Soluble | Slightly Soluble | X | X | X | Soluble | X |
Phenylmercuric Nitrate | Very Slightly Soluble | Slightly Soluble | X | X | X | X | X |
Phenyramidol Hydrochloride | Freely Soluble | Freely Soluble | X | X | Freely Soluble | X | X |
Phenytoin | Practically Insoluble | Slightly Soluble | X | X | X | X | Very Slightly Soluble |
Phenytoin Sodium | Soluble | Soluble | Practically Insoluble | X | X | X | Practically Insoluble |
Pholcodine | Sparingly Soluble | Freely Soluble | Slightly Soluble | Very Soluble | X | Very Soluble | X |
Phosphoric Acid | Soluble | Soluble | X | X | X | X | X |
Physostigmine Salicylate | Sparingly Soluble | Soluble | Very Slightly Soluble | Soluble | X | X | X |
Phytomenadione | Practically Insoluble | Sparingly Soluble | X | X | X | X | X |
Pilocarpine Nitrate | Freely Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Pimozide | Practically Insoluble | Sparingly Soluble | X | X | X | X | Soluble |
Pindolol | Practically Insoluble | X | X | Very Slightly Soluble | Slightly Soluble | X | X |
Pioglitazone Hydrochloride | Practically Insoluble | X | Practically Insoluble | X | X | X | X |
Piperacillin | Slightly Soluble | X | X | X | Freely Soluble | X | X |
Piperazine Adipate | Soluble | Practically Insoluble | X | X | X | X | X |
Piperazine Citrate | Freely Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Piperazine Hydrate | Freely Soluble | Freely Soluble | Slightly Soluble | X | X | X | X |
Piperazine Phosphate | Sparingly Soluble | Practically Insoluble | X | X | X | X | X |
Piracetam | Freely Soluble | Soluble | X | X | X | X | X |
Pirfenidone | X | X | X | X | Soluble | X | X |
Piroxicam | Very Slightly Soluble | Slightly Soluble | X | X | X | X | X |
Pitavastatin Calcium | X | X | X | X | X | X | X |
Plaster of Paris | Soluble | X | X | X | X | X | X |
Polacrilin Potassium | Practically Insoluble | X | X | X | X | X | X |
Poloxamers | Freely Soluble | Freely Soluble | X | X | X | X | X |
Polyethylene Glycol 1500 | Freely Soluble | Sparingly Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Polyethylene Glycol 4000 | Freely Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Polyethylene Glycol 6000 | Freely Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Polyoxy 35 Castor Oil | X | Very Soluble | X | X | X | X | X |
Polysorbate 20 | Soluble | Soluble | X | X | Soluble | X | X |
Polysorbate 80 | Soluble | Soluble | X | X | Soluble | X | X |
Polyvinyl Acetate Phthalate | Practically Insoluble | Soluble | X | Practically Insoluble | Soluble | X | Practically Insoluble |
Polyvinyl Alcohol | Soluble | Slightly Soluble | X | X | X | X | X |
Potassium Chloride | Freely Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Potassium Citrate | Very Soluble | Practically Insoluble | X | X | X | X | X |
Potassium Clavulanate | Freely Soluble | Slightly Soluble | X | X | X | Very Slightly Soluble | X |
Potassium Iodide | Very Soluble | Soluble | X | X | X | X | X |
Potassium Permanganate | Freely Soluble | X | X | X | X | X | X |
Potassium Sorbate | Very Soluble | Slightly Soluble | X | X | X | X | X |
Povidone | Freely Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Povidone Iodine | Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Pralidoxime Chloride | Freely Soluble | Sparingly Soluble | X | X | X | X | X |
Pravastatin Sodium | Freely Soluble | Soluble | X | X | Freely Soluble | X | X |
Praziquantel | Very Slightly Soluble | Freely Soluble | X | X | X | X | Freely Soluble |
Prazosin Hydrochloride | Very Slightly Soluble | Slightly Soluble | X | Practically Insoluble | Slightly Soluble | Practically Insoluble | X |
Prednisolone | Very Slightly Soluble | Soluble | X | Slightly Soluble | Soluble | Sparingly Soluble | X |
Prednisolone Acetate | Practically Insoluble | Slightly Soluble | X | X | X | X | Slightly Soluble |
Prednisolone Sodium Phosphate | Freely Soluble | Very Slightly Soluble | X | X | X | X | X |
Prednisone | Practically Insoluble | Slightly Soluble | X | Slightly Soluble | X | X | X |
Pregabalin | Sparingly Soluble | X | X | X | X | X | X |
Prilocaine | Slightly Soluble | Very Soluble | X | X | X | X | X |
Primaquine Phosphate | Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Probenecid | Practically Insoluble | Sparingly Soluble | Slightly Soluble | Sparingly Soluble | X | Soluble | X |
Procainamide Hydrochloride | Very Soluble | Freely Soluble | Practically Insoluble | Slightly Soluble | X | Slightly Soluble | X |
Procaine Hydrochloride | Very Soluble | Soluble | Practically Insoluble | Slightly Soluble | X | X | X |
Procaine Penicillin | Slightly Soluble | Sparingly Soluble | X | X | X | X | X |
Procarbazine Hydrochloride | Soluble | Sparingly Soluble | X | X | Soluble | X | X |
Prochlorperazine Maleate | Very Slightly Soluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Prochlorperazine Mesylate | Very Soluble | Sparingly Soluble | Practically Insoluble | Slightly Soluble | X | X | X |
Procyclidine Hydrochloride | Sparingly Soluble | Soluble | Practically Insoluble | X | X | Practically Insoluble | X |
Progesterone | Practically Insoluble | Freely Soluble | X | X | X | Sparingly Soluble | X |
Proguanil Hydrochloride | Slightly Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Promazine Hydrochloride | Freely Soluble | Freely Soluble | X | X | X | X | Freely Soluble |
Promethazine Hydrochloride | Very Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Promethazine Theoclate | Very Slightly Soluble | Sparingly Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Propionic Acid | X | Soluble | X | X | X | X | X |
Propofol | Very Slightly Soluble | X | X | X | Soluble | X | X |
Propranolol Hydrochloride | Soluble | Soluble | Practically Insoluble | Slightly Soluble | X | X | X |
Propyl Gallate | Very Slightly Soluble | Soluble | Soluble | X | X | X | X |
Propylene Glycol | Soluble | Soluble | X | Soluble | X | Soluble | X |
Propylene Glycol Monocaprylate | Practically Insoluble | Very Soluble | X | Very Soluble | X | X | X |
Propyliodone | Practically Insoluble | Soluble | Soluble | X | X | Soluble | X |
Propylparaben | Slightly Soluble | Freely Soluble | Freely Soluble | X | Freely Soluble | Freely Soluble | X |
Propylthiouracil | Very Slightly Soluble | Sparingly Soluble | Very Slightly Soluble | X | Sparingly Soluble | X | X |
Propyphenazone | Slightly Soluble | Freely Soluble | Soluble | X | X | X | Freely Soluble |
Protamine Sulphate | Sparingly Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Prothionamide | Practically Insoluble | Soluble | Slightly Soluble | Slightly Soluble | Soluble | X | X |
Protriptyline Hydrochloride | Freely Soluble | Freely Soluble | Practically Insoluble | X | X | X | X |
Pseudoephedrine Hydrochloride | Very Soluble | Freely Soluble | X | Sparingly Soluble | X | X | X |
Psoralen | X | Soluble | Sparingly Soluble | Very Soluble | X | X | X |
Pyrantel Pamoate | Practically Insoluble | X | X | X | Practically Insoluble | X | X |
Pyrazinamide | Sparingly Soluble | Slightly Soluble | Very Slightly Soluble | Sparingly Soluble | X | X | X |
Pyridostigmine Bromide | Freely Soluble | Freely Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Pyridoxine Hydrochloride | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Pyrimethamine | Practically Insoluble | Slightly Soluble | Very Slightly Soluble | Slightly Soluble | X | X | X |
Quetiapine Fumarate | X | X | X | X | Sparingly Soluble | X | X |
Quinalbarbitone Sodium | Freely Soluble | Freely Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Quinidine Sulphate | Sparingly Soluble | Soluble | Practically Insoluble | Soluble | X | X | X |
Quinine Bisulphate | Soluble | Sparingly Soluble | X | Slightly Soluble | X | X | X |
Quinine Dihydrochloride | Very Soluble | Soluble | Very Slightly Soluble | Slightly Soluble | X | X | X |
Quinine Sulphate | Slightly Soluble | X | Practically Insoluble | Very Slightly Soluble | X | X | X |
Quiniodochlor | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Rabeprazole Sodium | Soluble | X | X | X | X | X | X |
Racecadotril | Practically Insoluble | X | X | X | Freely Soluble | X | Freely Soluble |
Rafoxanide | Practically Insoluble | X | X | X | Slightly Soluble | Soluble | Sparingly Soluble |
Raloxifene Hydrochloride | Very Slightly Soluble | Slightly Soluble | Practically Insoluble | X | Sparingly Soluble | X | X |
Ramelteon | Practically Insoluble | X | X | X | Soluble | X | X |
Ramipril | Sparingly Soluble | X | X | X | Freely Soluble | X | X |
Ranitidine Hydrochloride | Freely Soluble | Sparingly Soluble | X | Very Slightly Soluble | Soluble | X | Very Slightly Soluble |
Purified Rayon | X | X | X | X | X | X | X |
Rebamipide | Practically Insoluble | X | X | X | Slightly Soluble | X | X |
Repaglinide | Practically Insoluble | X | X | X | Freely Soluble | X | Freely Soluble |
Reserpine | Practically Insoluble | Very Slightly Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Ribavirin | Freely Soluble | Slightly Soluble | X | X | X | X | Very Slightly Soluble |
Riboflavine | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X |
Riboflavine Sodium Phosphate | Soluble | Very Slightly Soluble | Practically Insoluble | X | X | X | X |
Rifampicin | Slightly Soluble | Slightly Soluble | Slightly Soluble | Soluble | Soluble | Slightly Soluble | X |
Rilpivirine | X | X | X | X | X | X | X |
Risedronate Sodium | Soluble | X | X | X | X | X | X |
Ritodrine Hydrochloride | Freely Soluble | Soluble | Practically Insoluble | X | X | Practically Insoluble | X |
Ritonavir | X | Freely Soluble | X | X | Freely Soluble | X | X |
Rizatriptan Benzoate | Soluble | Slightly Soluble | X | X | Soluble | X | Slightly Soluble |
Roflumilast | X | X | X | X | X | Practically Insoluble | X |
Ronidazole | Slightly Soluble | Slightly Soluble | Very Slightly Soluble | X | X | X | Slightly Soluble |
Ropivacaine Hydrochloride | Soluble | X | X | X | X | X | X |
Rosuvastatin Calcium | X | X | X | X | X | Soluble | X |
Roxithromycin | Very Slightly Soluble | Freely Soluble | X | X | X | Freely Soluble | Freely Soluble |
Rufinamide | Practically Insoluble | X | X | X | Slightly Soluble | X | X |
Rupatadine Fumarate. | X | X | X | X | Sparingly Soluble | X | X |
Saccharin. | Sparingly Soluble | Sparingly Soluble | Slightly Soluble | Slightly Soluble | X | X | X |
Saccharin Sodium | Freely Soluble | Sparingly Soluble | Practically Insoluble | X | X | X | X |
Safinamide Methane Sulphonate | Soluble | X | X | X | Soluble | X | X |
Salbutamol | Sparingly Soluble | Soluble | Slightly Soluble | X | X | X | X |
Salbutamol Sulphate | Freely Soluble | Slightly Soluble | Slightly Soluble | X | X | X | Very Slightly Soluble |
Salicylic Acid | Slightly Soluble | Freely Soluble | Freely Soluble | Sparingly Soluble | X | X | X |
Salmeterol Xinafoate | Practically Insoluble | X | X | X | Soluble | X | X |
Saquinavir | X | X | X | X | Soluble | X | X |
Saquinavir Mesylate | X | X | X | X | Soluble | X | X |
Selegiline Hydrochloride | Freely Soluble | X | X | X | Freely Soluble | Slightly Soluble | X |
Secnidazole | Slightly Soluble | Very Soluble | X | Very Soluble | Very Soluble | X | X |
Seratrodast | X | X | X | X | X | X | X |
Sertaconazole Nitrate | Practically Insoluble | Sparingly Soluble | X | X | Soluble | X | X |
Sertraline Hydrochloride | Slightly Soluble | Sparingly Soluble | X | X | X | Slightly Soluble | X |
Shellac | Practically Insoluble | Soluble | X | X | X | X | X |
Sildenafil Citrate | X | X | X | X | Slightly Soluble | X | X |
Colloidal Silicon Dioxide | Practically Insoluble | X | X | X | X | X | X |
Silver Nitrate | Very Soluble | Soluble | X | X | X | X | X |
Silver Sulphadiazine | X | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | Slightly Soluble | X |
Simvastatin | Practically Insoluble | Freely Soluble | X | X | X | X | Very Soluble |
Sisomicin Sulphate | Soluble | X | X | X | Soluble | X | X |
Sitagliptin Phosphate | Soluble | Very Slightly Soluble | X | X | X | X | X |
Sodium Acetate | Very Soluble | Soluble | X | X | X | X | X |
Sodium Alendronate Trihydrate | Soluble | X | X | X | Practically Insoluble | X | X |
Sodium Alginate | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Sodium Aminosalicylate | Freely Soluble | Sparingly Soluble | Very Slightly Soluble | Very Slightly Soluble | X | X | X |
Sodium Ascorbat | Freely Soluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Sodium Benzoate | Freely Soluble | Sparingly Soluble | X | X | X | X | X |
Sodium Bicarbonate | Freely Soluble | Practically Insoluble | X | X | X | X | X |
Sodium Carbonate | Freely Soluble | Practically Insoluble | X | X | X | X | X |
Sodium Carboxymethyl Celluose | Soluble | Practically Insoluble | Practically Insoluble | X | X | Practically Insoluble | X |
Sodium Chloride | Freely Soluble | Practically Insoluble | X | X | X | X | X |
Sodium Citrate | Freely Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Sodium Diatrizoate | Freely Soluble | Slightly Soluble | Practically Insoluble | X | X | Practically Insoluble | X |
Sodium Fluoride | Soluble | Practically Insoluble | X | X | X | X | X |
Sodium Formaldehyde Sulphoxylate | Freely Soluble | Slightly Soluble | Slightly Soluble | Slightly Soluble | X | X | X |
Sodium Fusidate | Freely Soluble | Freely Soluble | Practically Insoluble | Slightly Soluble | X | Practically Insoluble | X |
Sodium Hydroxide | Sparingly Soluble | Freely Soluble | X | X | X | X | X |
Sodium Lauryl Sulphate | Freely Soluble | Slightly Soluble | X | X | X | X | X |
Sodium Metabisulphite | Freely Soluble | Slightly Soluble | X | X | X | X | X |
Sodium Methylparaben. | Freely Soluble | Sparingly Soluble | X | X | X | X | X |
Sodium Nitrite | Freely Soluble | Sparingly Soluble | X | X | X | X | X |
Sodium Nitroprusside | Freely Soluble | Slightly Soluble | X | X | X | X | X |
Monobasic Sodium Phosphate | Very Soluble | Very Slightly Soluble | X | X | X | X | X |
Sodium Phosphate | Very Soluble | Practically Insoluble | X | X | X | X | X |
Sodium Propylparaben | Freely Soluble | Sparingly Soluble | X | X | X | X | X |
Sodium Salicylate. | Freely Soluble | Freely Soluble | Practically Insoluble | X | X | X | X |
Sodium Starch Glycollate | Practically Insoluble | X | X | X | X | X | X |
Sodium Stibogluconate | Very Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Sodium Thiosulphate | Very Soluble | Practically Insoluble | X | X | X | X | X |
Sodium Valproate | Very Soluble | Very Soluble | Practically Insoluble | X | X | X | X |
Sorafenib Tosylate | Practically Insoluble | X | X | X | X | X | X |
Sorbic Acid | Slightly Soluble | Freely Soluble | Freely Soluble | X | X | X | X |
Sorbitan Oleate | Practically Insoluble | Soluble | X | X | X | X | X |
Sorbitol | Very Soluble | Sparingly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Sorbitol Solution (70 Per cent) (Non- crystallising) | Soluble | X | X | X | X | X | X |
Soyabean Oil | Practically Insoluble | Practically Insoluble | Soluble | Soluble | X | X | X |
Spectinomycin Hydrochloride | Soluble | Practically Insoluble | Practically Insoluble | X | X | X | Practically Insoluble |
Spiramycin | Slightly Soluble | Freely Soluble | Sparingly Soluble | X | Freely Soluble | Freely Soluble | X |
Spironolactone | Practically Insoluble | Soluble | Slightly Soluble | Freely Soluble | X | X | X |
Starch | Practically Insoluble | Slightly Soluble | X | X | X | X | X |
Stavudine | Soluble | Sparingly Soluble | X | X | X | X | Slightly Soluble |
Stearic Acid | Practically Insoluble | Soluble | Soluble | Soluble | X | X | X |
Stearyl Alcohol. | Practically Insoluble | Soluble | Freely Soluble | Freely Soluble | X | X | X |
Stilboestrol | Very Slightly Soluble | Freely Soluble | Freely Soluble | X | X | X | X |
Streptokinase | Freely Soluble | X | X | X | X | X | X |
Streptomycin Sulphate | Very Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Succinylcholine Chloride | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Sucralfate | Practically Insoluble | X | X | X | X | X | X |
Sucralose | Freely Soluble | Freely Soluble | X | X | Freely Soluble | X | X |
Sucrose | Very Soluble | Slightly Soluble | X | X | X | X | X |
Sulphacetamide Sodium | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Sulphadiazine | Practically Insoluble | Very Slightly Soluble | X | Practically Insoluble | Freely Soluble | Slightly Soluble | X |
Sulphadimidine | Very Slightly Soluble | Slightly Soluble | X | Very Soluble | X | Soluble | X |
Sulphadoxine | Very Slightly Soluble | Slightly Soluble | Practically Insoluble | X | Slightly Soluble | X | X |
Sulphamethizole | Very Slightly Soluble | Sparingly Soluble | Very Slightly Soluble | Very Slightly Soluble | X | Soluble | X |
Sulphamethoxazole | Practically Insoluble | Sparingly Soluble | Slightly Soluble | Slightly Soluble | X | Freely Soluble | X |
Sulphaquinoxaline. | Practically Insoluble | Very Slightly Soluble | Practically Insoluble | X | X | X | X |
Sulphathiazole Sodium | Freely Soluble | Soluble | X | X | X | X | X |
Sulpride | Practically Insoluble | Slightly Soluble | X | X | Sparingly Soluble | X | Slightly Soluble |
Sumatriptan | Very Slightly Soluble | X | X | X | X | X | X |
Sumatriptan Succinate | Freely Soluble | X | X | X | Sparingly Soluble | X | Practically Insoluble |
Tacrolimus | Practically Insoluble | Soluble | X | X | Soluble | X | X |
Tadalafil. | Practically Insoluble | X | X | X | X | X | Slightly Soluble |
Tafluprost | Practically Insoluble | X | X | X | X | X | X |
Talc | Practically Insoluble | X | X | X | X | X | X |
Tamoxifen Citrate | Very Slightly Soluble | Very Slightly Soluble | X | Very Slightly Soluble | Soluble | Very Slightly Soluble | X |
Tamsulosin Hydrochloride | Slightly Soluble | Slightly Soluble | X | X | X | X | X |
Tapentadol Hydrochloride | Freely Soluble | X | X | X | Freely Soluble | X | X |
Tartaric Acid | Very Soluble | Freely Soluble | X | X | X | X | X |
Tauroursodeoxycholic Acid | X | X | X | X | Soluble | X | X |
Tazobactam | Slightly Soluble | Slightly Soluble | Very Slightly Soluble | Very Slightly Soluble | Slightly Soluble | Slightly Soluble | X |
Teicoplanin | Freely Soluble | Practically Insoluble | X | X | X | X | X |
Telmisartan | Practically Insoluble | X | X | X | Slightly Soluble | X | Sparingly Soluble |
Temozolomide | Slightly Soluble | X | X | X | X | X | X |
Tenofovir Disoproxil Fumarate | Soluble | X | X | X | X | X | X |
Terazosin Hydrochloride | Sparingly Soluble | Very Slightly Soluble | X | X | Slightly Soluble | Practically Insoluble | X |
Terbinafine Hydrochloride | Slightly Soluble | Freely Soluble | X | X | Freely Soluble | Slightly Soluble | X |
Terbutaline Sulphate | Freely Soluble | Slightly Soluble | X | Practically Insoluble | X | X | X |
Testosterone Propionate | Practically Insoluble | Freely Soluble | X | Very Soluble | Freely Soluble | Freely Soluble | X |
Tetracycline | Very Slightly Soluble | Soluble | Practically Insoluble | Slightly Soluble | Soluble | Sparingly Soluble | X |
Tetracycline Hydrochloride | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Theophylline | Slightly Soluble | Sparingly Soluble | X | Slightly Soluble | X | X | X |
Thiabendazole | Practically Insoluble | Slightly Soluble | Slightly Soluble | Slightly Soluble | X | X | Slightly Soluble |
Thiacetazone | Very Slightly Soluble | Slightly Soluble | X | X | X | X | X |
Thiamine Hydrochloride | Freely Soluble | Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Thiamine Mononitrate | Sparingly Soluble | Slightly Soluble | X | X | Slightly Soluble | X | X |
Thiocolchicoside | Soluble | Very Slightly Soluble | X | X | X | X | X |
Thioguanine | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X | X | X |
Thiomersal. | Freely Soluble | Freely Soluble | Practically Insoluble | X | X | X | X |
Thiopentone Sodium | Freely Soluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Thiotepa | Freely Soluble | Freely Soluble | Freely Soluble | Freely Soluble | X | X | X |
Thyme Oil. | X | X | X | X | X | X | X |
Thymol | Very Slightly Soluble | Very Soluble | Very Soluble | X | X | X | X |
Thyroxine Sodium | Very Slightly Soluble | Slightly Soluble | Practically Insoluble | X | X | X | X |
Tibolone | Practically Insoluble | X | X | X | Soluble | Soluble | X |
Ticagrelor | Sparingly Soluble | X | X | X | Soluble | X | X |
Timolol Maleate | Soluble | Soluble | Practically Insoluble | Sparingly Soluble | X | X | X |
Tinidazole | Practically Insoluble | Slightly Soluble | X | Slightly Soluble | Sparingly Soluble | Soluble | Soluble |
Tiotropium Bromide Monohydrate | Sparingly Soluble | X | X | X | Soluble | X | X |
Titanium Dioxide | Practically Insoluble | X | X | X | X | X | X |
Tizanidine Hydrochloride | Slightly Soluble | X | X | X | Slightly Soluble | X | X |
Tobramycin. | Freely Soluble | Very Slightly Soluble | Practically Insoluble | Practically Insoluble | X | X | X |
Tocopheryl Acetate | Practically Insoluble | Soluble | Freely Soluble | Freely Soluble | X | Freely Soluble | X |
Tolazamide | Very Slightly Soluble | Slightly Soluble | X | Freely Soluble | X | Soluble | X |
Tolbutamide | Practically Insoluble | Soluble | Slightly Soluble | Soluble | X | Soluble | X |
Tolnaftate. | Practically Insoluble | Very Slightly Soluble | X | X | X | Freely Soluble | Freely Soluble |
Tolterodine Tartrate | X | Slightly Soluble | X | X | Sparingly Soluble | X | X |
Tolvaptan | Practically Insoluble | Freely Soluble | X | X | Soluble | X | X |
Tolu Balsam | Practically Insoluble | Freely Soluble | Freely Soluble | Freely Soluble | X | X | X |
Topiramate | Slightly Soluble | Freely Soluble | X | X | X | X | X |
Topotecan Hydrochloride. | Soluble | X | X | X | X | X | X |
Torsemide | Practically Insoluble | Slightly Soluble | Practically Insoluble | Very Slightly Soluble | Slightly Soluble | Very Slightly Soluble | X |
Tramadol Hydrochloride | Freely Soluble | X | X | X | Freely Soluble | Very Slightly Soluble | X |
Trandolapril | X | X | X | Soluble | Soluble | X | Soluble |
Tranexamic Acid | Freely Soluble | Practically Insoluble | X | X | X | Practically Insoluble | X |
Tranilast | Practically Insoluble | Soluble | X | X | X | X | X |
Travoprost | Practically Insoluble | Very Soluble | X | Very Soluble | Very Soluble | X | X |
Triamcinolone | Slightly Soluble | Sparingly Soluble | Very Slightly Soluble | Very Slightly Soluble | X | X | X |
Triamcinolone Acetonide | Practically Insoluble | Sparingly Soluble | Very Slightly Soluble | Sparingly Soluble | X | X | X |
Triamterene | Practically Insoluble | Very Slightly Soluble | X | Very Slightly Soluble | X | X | X |
Trichloromonofluoromethane | Practically Insoluble | Soluble | Soluble | X | X | X | X |
Triclofos Sodium | Freely Soluble | Slightly Soluble | Practically Insoluble | X | X | X | X |
Triethyl Citrate | Soluble | Soluble | X | X | X | X | X |
Tributyl Citrate | Practically Insoluble | Soluble | X | X | X | Freely Soluble | X |
Trifluoperazine Hydrochloride | Freely Soluble | Soluble | Practically Insoluble | Slightly Soluble | X | X | X |
Triflupromazine Hydrochloride | Soluble | Soluble | Practically Insoluble | X | X | Soluble | X |
Trifluridine | Soluble | X | X | X | X | X | X |
Trimebutine Maleate. | Slightly Soluble | Slightly Soluble | X | X | X | Sparingly Soluble | X |
Trimetazidine Hydrochloride | Freely Soluble | Sparingly Soluble | X | X | X | X | X |
Trimethobenzamide Hydrochloride | Soluble | Soluble | Practically Insoluble | X | X | X | X |
Trimethoprim | Very Slightly Soluble | Slightly Soluble | Practically Insoluble | Sparingly Soluble | X | X | X |
Triprolidine Hydrochloride. | Freely Soluble | Freely Soluble | Practically Insoluble | Very Soluble | X | X | X |
Tropicamide. | Slightly Soluble | Freely Soluble | X | Freely Soluble | X | X | X |
Trospium Chloride | Very Soluble | X | X | X | Freely Soluble | X | Practically Insoluble |
Troxidone | Soluble | Very Soluble | Very Soluble | Very Soluble | X | X | X |
Tubocurarine Chloride | Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | Practically Insoluble | X |
Tylosin | Slightly Soluble | Soluble | X | X | Freely Soluble | X | Soluble |
Tylosin Tartrate | Freely Soluble | Slightly Soluble | Practically Insoluble | X | X | X | Freely Soluble |
Tyrothricin | Practically Insoluble | Soluble | X | X | Soluble | X | X |
Ulipristal Acetate | Practically Insoluble | Soluble | X | X | Soluble | Soluble | Freely Soluble |
Undecenoic Acid | Practically Insoluble | Freely Soluble | Freely Soluble | Freely Soluble | X | X | X |
Urea | Freely Soluble | Soluble | Practically Insoluble | Practically Insoluble | X | X | Practically Insoluble |
Urokinase | Soluble | X | X | X | X | X | X |
Ursodeoxycholic Acid | Practically Insoluble | Freely Soluble | X | X | X | Slightly Soluble | Practically Insoluble |
Valproic Acid | Slightly Soluble | X | X | X | X | X | X |
Valsartan | Practically Insoluble | X | X | X | Very Soluble | X | X |
Vancomycin Hydrochloride | Freely Soluble | Slightly Soluble | X | X | X | X | X |
Vanillin | Slightly Soluble | Freely Soluble | Soluble | X | Freely Soluble | X | X |
Vasopressin | Soluble | X | X | X | X | X | X |
Vecuronium Bromide | Slightly Soluble | Sparingly Soluble | X | X | X | X | Freely Soluble |
Verapamil Hydrochloride | Soluble | Sparingly Soluble | Practically Insoluble | Freely Soluble | X | X | X |
Vinblastine Sulphate | Freely Soluble | Practically Insoluble | Practically Insoluble | X | Soluble | X | X |
Vincristine Sulphate | Freely Soluble | Slightly Soluble | Practically Insoluble | X | Soluble | X | X |
Vinorelbine Tartrate. | Freely Soluble | X | X | X | X | X | X |
Vitamin A Concentrate (Oily Form) | Practically Insoluble | Soluble | X | X | X | X | X |
Vitamin A Concentrate (Powder Form). | Practically Insoluble | X | X | X | X | X | X |
Voglibose | Soluble | X | X | X | Slightly Soluble | X | X |
Voriconazole | Very Slightly Soluble | X | X | X | X | Freely Soluble | Freely Soluble |
Warfarin Sodium | Very Soluble | Very Soluble | Very Slightly Soluble | X | X | Soluble | Very Slightly Soluble |
Warfarin Sodium Clathrate | Very Soluble | Freely Soluble | Very Slightly Soluble | X | X | X | Very Slightly Soluble |
Wool Fat | Practically Insoluble | Slightly Soluble | Soluble | Soluble | X | X | X |
Hydrous Wool Fat | Practically Insoluble | Slightly Soluble | Soluble | Soluble | X | X | X |
Xanthan Gum | Soluble | X | X | X | X | X | X |
Xylazine Hydrochloride | Freely Soluble | X | X | X | Very Soluble | X | X |
Xylometazoline Hydrochloride | Soluble | Freely Soluble | Practically Insoluble | Soluble | X | X | X |
Xylose | Very Soluble | Soluble | X | X | X | X | X |
Zidovudine | Sparingly Soluble | Soluble | X | X | Soluble | X | X |
Zinc Chloride. | Very Soluble | Freely Soluble | X | X | X | X | X |
Zinc Oxide | Practically Insoluble | Practically Insoluble | X | X | X | X | X |
Zinc Stearate | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Zinc Sulphate. | Very Soluble | Practically Insoluble | X | X | X | X | X |
Zinc Sulphate Monohydrate | Very Soluble | Practically Insoluble | X | X | X | X | X |
Zinc Undecenoate | Practically Insoluble | Practically Insoluble | Practically Insoluble | X | X | X | X |
Ziprasidone Hydrochloride Monohydrate | Practically Insoluble | X | X | X | Slightly Soluble | X | Slightly Soluble |
Zoledronic Acid | Slightly Soluble | X | X | X | X | X | X |
Zolmitriptan | Soluble | Soluble | X | Slightly Soluble | Freely Soluble | Soluble | Sparingly Soluble |
Zolpidem Tartrate | Slightly Soluble | X | X | X | Sparingly Soluble | X | Practically Insoluble |
Zonisamide | X | X | X | X | Soluble | X | X |
Zopiclone | Practically Insoluble | Practically Insoluble | X | X | X | Sparingly Soluble | Freely Soluble |
Zuclopenthixol Acetate | Very Slightly Soluble | Very Soluble | Very Soluble | X | X | X | Very Soluble |